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	Provedor de dados 52 (2) Autor Kalender,Yusuf (2) Aslanturk,Ayse (1) Celikoglu,Emine (1) Karaboduk,Hatice (1) Uzunhisarcikli,Meltem (1) Palavra-chave Mercuric chloride (2) Sodium selenite (2) Vitamin E (2) Cardiotoxicity (1) Histopathology (1) Lung toxicity (1) Oxidative Stress (1) Oxidative stress (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2015 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Vitamin E and Sodium Selenite Against Mercuric Chloride-Induced Lung Toxicity in the Rats 52 Celikoglu,Emine; Aslanturk,Ayse; Kalender,Yusuf. The aim of the present study was to elucidate the possible protective role of vitamin E and / or sodium selenite on mercuric chloride-induced oxidative stress and histopathological changes in the lung tissue of the rats. Adult male albino Wistar rats were exposed to mercuric chloride (1.0 mg/kg day) for four weeks. Treatment with mercuric chloride led to oxidative stress by enhancing MDA level and also decreasing superoxide dismutase (SOD), catalase (CAT) glutathione peroxidase (GPx) and glutathione S transferaz (GST) activities. However, mercuric chloride exposure resulted in histopathological changes in the lung tissue in the rats. MDA level and SOD, CAT GPx and GST activities and histopathological changes modulated in concomitantly supplementation of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mercuric chloride; Sodium selenite; Vitamin E; Lung toxicity; Oxidative stress; Histopathology. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400587 Protective Effects of Sodium Selenite and Vitamin E on Mercuric Chloride-Induced Cardiotoxicity in Male Rats 52 Karaboduk,Hatice; Uzunhisarcikli,Meltem; Kalender,Yusuf. This study was designed to investigate the protective effects of sodium selenite and/or vitamin E against mercuric chloride-induced cardiotoxicity. Male Wistar rats (n=48, 310±10 g) were administered mercuric chloride (1.0 mg/kg bw), sodium selenite (0.25 mg/kg bw), vitamin E (100 mg/kg bw), sodium selenite plus mercuric chloride, vitamin E plus mercuric chloride and sodium selenite plus vitamin E plus mercuric chloride daily via gavage for four weeks. Malondialdehyde (MDA) level, antioxidant enzyme activities [total superoxide dismutase (SOD), catalase (CAT), total glutathione peroxidase (GPx) and total glutathione-S-transferase (GST)], and histopathological changes in the heart tissue were evaluated. Results showed that mercuric chloride exposure... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mercuric chloride; Sodium selenite; Vitamin E; Cardiotoxicity; Oxidative Stress. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000200229 Registros recuperados: 2 Primeira ... 1 ... Última

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