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Presence of highly oncogenic human papillomavirus in the oral mucosa of asymptomatic men BJID
Machado,Ana Paula; Almeida,Flávia Gatto de; Bonin,Camila Mareti; Prata,Thiago Theodoro Martins; Ávilla,Leandro Sobrinho; Padovani,Cacilda Tezelli Junqueira; Ferreira,Alda Maria Teixeira; Fernandes,Carlos Eurico dos Santos; Tozetti,Inês Aparecida.
OBJECTIVES: The aim of this study was to identify highly oncogenic forms of human papillomavirus in the oral mucosa of asymptomatic men.METHODS: In this study, we analyzed samples of exfoliated cells from the oral cavity of 559 asymptomatic men. DNA-human papillomavirus was detected using the consensus primers PGMY09/11; viral genotyping was performed using type-specific PCR and restriction fragment length polymorphism.RESULTS: DNA-human papillomavirus was detected in 1.3% of the study participants and of those 42.8% were infected by more than one type of virus. Viral types included HPV6, 11, 89 (low oncogenic risk), and HPV52, 53 (high oncogenic risk). Increased vulnerability to human papillomavirus infection was observed in individuals aged over 26...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papilomavírus; Men; Viral type; Oral mucosal.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000300266
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