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Does Cimicifuga racemosa have the effects like estrogen on the sublingual gland in ovariectomized rats? Biol. Res.
Da,Yun‑Meng; Niu,Kai‑Yu; Liu,Shu‑Ya; Wang,Ke; Wang,Wen‑Juan; Jia,Jing; Qin,Li‑Hua; Bai,Wen‑Pei.
Abstract Background Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen. Apart from hectic fevers, dyspareunia and so on, dry mouth also increase significantly after menopause. It has not yet been reported whether C. racemosa has any impact on the sublingual gland, which may relate to dry mouth. In an attempt to determine this, we have compared the effects of estrogen and C. racemosa on the sublingual gland of ovariectomized rats. Results HE staining showed that the acinar cell area had contracted and that the intercellular spaces were broadened in the OVX (ovariectomized rats) group, while treatment with estradiol (E2) and iCR (isopropanolic extract of C....
Tipo: Journal article Palavras-chave: Estradiol; Cimicifuga racemosa; Sublingual gland; Subcellular structure; Caspase-3.
Ano: 2017 URL:
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