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	Provedor de dados BJMBR (2) Autor Carvalho,M.H.C. (1) Dantas,A.P.V. (1) Francisco,Y.A. (1) Franco,M. (1) Janicki,J.S. (1) Laurindo,F.R.M. (1) Matsubara,B.B. (1) Matsubara,L.S. (1) Mais... Palavra-chave Vascular remodeling (2) Aldosterone (1) Dihydropyridine (1) Endothelial function (1) Estrogen (1) Fibrinoid necrosis (1) Hypertension (1) Myocardial remodeling (1) Nitric oxide (1) Restenosis post-angioplasty (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2010 (1) 2005 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats BJMBR Matsubara,B.B.; Franco,M.; Janicki,J.S.; Matsubara,L.S.. It has been recently shown that calcium channel blockers might have a protective effect on cardiac fibrogenesis induced by aldosterone. The objective of this study was to evaluate the protective effect of felodipine, a dihydropyridine calcium channel blocker, against heart and kidney damage caused by aldosterone-high sodium intake in uninephrectomized rats. Wistar rats were divided into three groups: CNEP (uninephrectomized + 1% NaCl in the drinking water, N = 9); ALDO (same as CNEP group plus continuous infusion of 0.75 µg/h aldosterone, N = 12); ALDOF (same as ALDO group plus 30 mg·kg-1·day-1 felodipine in the drinking water, N = 10). All results were compared with those of age-matched, untreated rats (CTL group, N = 10). After 6 weeks, tail cuff blood... Tipo: Info:eu-repo/semantics/article Palavras-chave: Aldosterone; Dihydropyridine; Fibrinoid necrosis; Vascular remodeling; Hypertension; Myocardial remodeling. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000500013 Estrogen enhances vasoconstrictive remodeling after injury in male rabbits BJMBR Francisco,Y.A.; Dantas,A.P.V.; Carvalho,M.H.C.; Laurindo,F.R.M.. The complete spectrum of estrogen vascular effects remains unclear. In particular, estrogen effects in the vascular response to profound injury in males have not been explored in detail. Therefore, we submitted 44 male New Zealand rabbits weighing 3.4 ± 0.6 kg to overdistention balloon injury of the right iliac artery. Rabbits were given 17ß-estradiol (5.45 µmol/day, sc) or vehicle for 7 days before and 14 days after injury, when the arteries were examined by post-mortem histomorphometry. Arteriographic caliber was assessed in vivo at baseline and before sacrifice. On day 14 after injury, in vivo arteriographic caliber (baseline = 2.44 ± 0.43 mm) was decreased by 23.1 ± 0.1% in controls and by 44.5 ± 0.1% in estrogen-treated rabbits (P < 0.001). Neither... Tipo: Info:eu-repo/semantics/other Palavras-chave: Estrogen; Restenosis post-angioplasty; Nitric oxide; Endothelial function; Vascular remodeling. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000900006 Registros recuperados: 2 Primeira ... 1 ... Última

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