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	Provedor de dados BABT (2) Autor Abdelbaky,Nayira (2) Al-Rasheed,Nawal (2) Al-Rasheed,Nouf (2) Faddah,Laila (2) Mohamed,Azza M (2) Ibrahim,Hanan (1) Sharaf,Iman A (1) Mais... Palavra-chave Carbon Tetrachloride (1) Cardiotoxicity (1) Carnosine (1) Curcumin (1) Melatonin (1) Silymarin (1) Titanium dioxide nanoparticles (1) Vitamin E (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2015 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Assessment of the Potential Role of Silymarin Alone or in Combination with Vitamin E and/ or Curcumin on the Carbon Tetrachloride Induced Liver Injury in Rat BABT Al-Rasheed,Nouf; Faddah,Laila; Sharaf,Iman A; Mohamed,Azza M; Al-Rasheed,Nawal; Abdelbaky,Nayira. ABSTRACT The aim of this study was to investigate the effective role of silymarin either alone or in a combination with vitamin E and/or curcumin against the toxic impact of carbon tetrachloride (CCl4) induced liver injury The results revealed that administration of silymarin alone or in a combination with vitamin E and/or curcumin for 21 consecutive days, 24 h after CCl4 injection to rats, markedly ameliorated DNA damaged and apoptosis markers in rat livers, proinflammatory markers including tumor necrosis factor- α (TNF- α) and C-reactive protein (CRP ) in rat livers as well as interleukin 6 (IL-6), interferon gamma (IFN-γ) and vascular endothelial growth factor (VEGF) in rat sera. These treatments also could ameliorated the alteration in cytochrome P450... Tipo: Info:eu-repo/semantics/article Palavras-chave: Silymarin; Vitamin E; Curcumin; Carbon Tetrachloride. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000600833 Role of Carnosine and Melatonin in Ameliorating Cardiotoxicity of Titanium Dioxide Nanoparticles in the Rats BABT Al-Rasheed,Nouf; Faddah,Laila; Ibrahim,Hanan; Mohamed,Azza M; Al-Rasheed,Nawal; Abdelbaky,Nayira. The aim of this work was to study the possible cardiotoxicity of two different doses of 50 nm nano titanium dioxide (n-TiO2) and the possible modulating effects of the use of two natural antioxidants carnosine and melatonin. The results showed that TiO2- NPs produced deleterious effects on rat cardiac tissue as confirmed by the increased levels of serum myoglobin, troponin-T and CK-MB. Increased levels of serum Inflammatory markers represented by the tumor necrosis factor alpha (TNF-α) and Interleukin-6 (IL-6) was also noticed. Caspase3 and IGg were elevated compared to the control group in a dose dependant manner. treatment of the rats with Carnosine or melatonin. along with TiO2- NPs administration significantly improved most of the elevated biochemical... Tipo: Info:eu-repo/semantics/article Palavras-chave: Titanium dioxide nanoparticles; Cardiotoxicity; Carnosine; Melatonin. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400577 Registros recuperados: 2 Primeira ... 1 ... Última

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