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	Provedor de dados 56 (2) Autor Ariga,S. (2) Barbeiro,H.V. (1) Curi,R. (1) Goloubkova,T. (1) Lima,J.P. (1) Melo,E.S. (1) Schochat,E. (1) Soriano,F.G. (1) Vasconcelos,D. (1) Velasco,I. (1) Velasco,I.T. (1) Mais... Palavra-chave Anesthetics (1) Auditory brainstem response (1) Auditory-evoked potential (1) Cytokines (1) Immune tolerance (1) Ketamine (1) Lipopolysaccharide (1) Murine sepsis model (1) Sepsis (1) T helper cells (1) Xylazine (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Effect of the ketamine/xylazine anesthetic on the auditory brainstem response of adult gerbils 56 Lima,J.P.; Ariga,S.; Velasco,I.; Schochat,E.. The auditory brainstem response (ABR) is a test widely used to assess the integrity of the brain stem. Although it is considered to be an auditory-evoked potential that is influenced by the physical characteristics of the stimulus, such as rate, polarity and type of stimulus, it may also be influenced by the change in several parameters. The use of anesthetics may adversely influence the value of the ABR wave latency. One of the anesthetics used for e ABR assessment, especially in animal research, is the ketamine/xylazine combination. Our objective was to determine the influence of the ketamine/xylazine anesthetic on the ABR latency values in adult gerbils. The ABRs of 12 adult gerbils injected with the anesthetic were collected on three consecutive days,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Auditory-evoked potential; Auditory brainstem response; Anesthetics; Ketamine; Xylazine. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200019 Immune cells and oxidative stress in the endotoxin tolerance mouse model 56 Melo,E.S.; Barbeiro,H.V.; Ariga,S.; Goloubkova,T.; Curi,R.; Velasco,I.T.; Vasconcelos,D.; Soriano,F.G.. Sepsis is a systemic inflammatory response that can lead to tissue damage and death. In order to increase our understanding of sepsis, experimental models are needed that produce relevant immune and inflammatory responses during a septic event. We describe a lipopolysaccharide tolerance mouse model to characterize the cellular and molecular alterations of immune cells during sepsis. The model presents a typical lipopolysaccharide tolerance pattern in which tolerance is related to decreased production and secretion of cytokines after a subsequent exposure to a lethal dose of lipopolysaccharide. The initial lipopolysaccharide exposure also altered the expression patterns of cytokines and was followed by an 8- and a 1.5-fold increase in the T helper 1 and 2... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sepsis; Cytokines; Immune tolerance; Lipopolysaccharide; Murine sepsis model; T helper cells. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000100009 Registros recuperados: 2 Primeira ... 1 ... Última

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