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Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial BJMBR
Souza,E.V.; Torloni,M.R.; Atallah,A.N.; dos Santos,G.M.S.; Kulay Jr,L.; Sass,N..
Preeclampsia is an important cause of maternal and perinatal morbidity and mortality. Previous studies have tested calcium supplementation and aspirin separately to reduce the incidence of preeclampsia but not the effects of combined supplementation. The objective of this study was to investigate the effectiveness of aspirin combined with calcium supplementation to prevent preeclampsia in women with chronic hypertension. A double-blind, placebo-controlled randomized clinical trial was carried out at the antenatal clinic of a large university hospital in São Paulo, SP, Brazil. A total of 49 women with chronic hypertension and abnormal uterine artery Doppler at 20-27 weeks gestation were randomly assigned to receive placebo (N = 26) or 100 mg aspirin plus 2...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Preeclampsia; Hypertension; Ultrasonography; Doppler; Calcium carbonate; Aspirin.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000500419
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Diet plus insulin compared to diet alone in the treatment of gestational diabetes mellitus: a systematic review BJMBR
Giuffrida,F.M.A.; Castro,A.A.; Atallah,A.N.; Dib,S.A..
Fetuses of mothers with gestational diabetes mellitus are at increased risk to develop perinatal complications mainly due to macrosomia. However, in view of the marked heterogeneity of this disease, it seems difficult to set guidelines for diagnosis and treatment. This complicates the choice of assigning patients either to diet or to insulin therapy. Also of concern is how much benefit could be expected from insulin therapy in preventing fetal complications in these patients. In a systematic review of the literature assessing the efficacy of insulin in preventing macrosomia in fetuses of mothers with gestational diabetes, we found six randomized controlled trials comparing diet alone to diet plus insulin. The studies included a total of 1281 patients (644...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Diabetes; Gestational; Diet therapy; Fetal macrosomia; Insulin; Meta-analysis.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000004
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