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	Provedor de dados BJMBR (2) Autor Boim,M.A. (2) Schor,N. (2) Andrade,A.Q. (1) Casarini,D.E. (1) Pereira,A.B. (1) Stella,S.R. (1) Mais... Palavra-chave Catecholamines (1) Glomerular function (1) Hanssen technique (1) Intrarenal blood flow (1) Kidney (1) Mesangial cell (1) Micropuncture (1) Prorenin (1) Renin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2002 (1) 1997 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Characterization of renin mRNA expression and enzyme activity in rat and mouse mesangial cells BJMBR Andrade,A.Q.; Casarini,D.E.; Schor,N.; Boim,M.A.. Renin is an enzyme involved in the stepwise generation of angiotensin II. Juxtaglomerular cells are the main source of plasma renin, but renin activity has been detected in other cell types. In the present study we evaluated the presence of renin mRNA in adult male Wistar rat and mouse (C-57 Black/6) mesangial cells (MC) and their ability to process, store and release both the active and inactive forms of the enzyme. Active renin and total renin content obtained after trypsin treatment were estimated by angiotensinogen consumption analyzed by SDS-PAGE electrophoresis and quantified by angiotensin I generation by HPLC. Renin mRNA, detected by RT-PCR, was present in both rat and mouse MC under basal conditions. Active renin was significantly higher... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin; Prorenin; Mesangial cell; Kidney. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100003 Heterogeneity of glomerular perfusion and filtration induced by epinephrine and norepinephrine BJMBR Boim,M.A.; Stella,S.R.; Pereira,A.B.; Schor,N.. The role of catecholamines in the distribution of intrarenal blood flow and in single-nephron glomerular filtration rate (SNGFR) was evaluated in anesthetized Wistar rats by the Hanssen technique. Epinephrine (EPI) and norepinephrine (NOR) were infused to produce elevations of 20-30 mmHg in mean arterial pressure. Superficial and juxtamedullary nephron perfusion and filtration were determined by the presence of Prussian blue dye. In the control group, 100% of the nephrons presented a homogeneous pattern of perfusion and filtration. In contrast, a heterogeneous distribution of the dye was found even in the larger arteries (arciform and radial), indicating variable perfusion and filtration in both superficial and juxtamedullary nephrons. The effects of EPI... Tipo: Info:eu-repo/semantics/article Palavras-chave: Catecholamines; Intrarenal blood flow; Glomerular function; Hanssen technique; Micropuncture. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800017 Registros recuperados: 2 Primeira ... 1 ... Última

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