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| CAMARGOS, A.; WOHLRES-VIANA, S.; COSTA, I. F.; CAMARGO, L. S. de A.; FERREIRA, J. C.; RAMOS, A. A.; OBA, E.. |
| ABSTRACT The present study investigated the hormonal profile and expression of prostaglandin F2? (PGF2?), oxytocin and estrogen receptors in uterine tissues of postpartum cows treated with cloprostenol. Twenty HolsteinZebu crossbred cows were treated with saline solution (treatment CONT) or cloprostenol (treatment CLO), both administered two and five days postpartum. Blood samples were collected on days two, seven, 14, 21 and 28 postpartum for progesterone, PGF2? metabolite (PGFM) and estradiol determination, and endometrial biopsy was performed in order to quantify the expression of oxytocin receptor (OXTR), prostaglandin F receptor (PTGFR) and estrogen receptor 1 (ERS1) genes. In the CLO treatment, expression of OXTR was reduced (P<0.05) but no... |
| Tipo: Separatas |
Palavras-chave: PTGFR; ESRI; RT-PCR.; Estradiol.; Progesterone.. |
| Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1085645 |
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| SILVA, D. T. da; SMANIOTTO, F. A.; COSTA, I. F.; BARANZELLI, J.; MULLER, A.; SOMACAL, S.; MONTEIRO, C. S.; VIZZOTTO, M.; RODRIGUES, E.; BARCIA, M. T.; EMANUELLI, T.. |
| This study investigated whether a ready-to-use extract obtained using a natural deep eutectic solvent (NADES) affects the pharmacokinetic profile of blueberry phenolic compounds compared to organic solvent (SORG)-extracted compounds. SORG extract was administered as an aqueous solution after solvent removal. Wistar rats received a single dose of crude extract of blueberry obtained using NADES (CE-NADES) or SORG (CE-SORG), followed by LC-DAD-MS/MS analysis of blood and cecal feces. Non-compartmental pharmacokinetic analysis revealed that CE-NADES increased the bioavailability of anthocyanins by 140% compared to CE-SORG. CE-NADES increased the stability of phenolic compounds during in vitro digestion by delaying gastric chyme neutralization. These results... |
| Tipo: Artigo de periódico |
Palavras-chave: Composto; Mirtilo; Extrato. |
| Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1138030 |
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