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	Provedor de dados BJID (2) Autor Cheinquer,Hugo (2) Brandão-Mello,Carlos Eduardo (1) Cheinquer,Nelson (1) Coelho,Henrique Sérgio Moraes (1) Coelho-Borges,Silvia (1) Estes,Chris (1) Ferraz,Maria Lúcia Gomes (1) Ferreira,Paulo Roberto Abrão (1) Gonçales Júnior,Fernando Lopes (1) Mendes-Correa,Maria Cássia (1) Pessoa,Mário Guimarães (1) Razavi,Homie (1) Wolff,Fernando H (1) Wolff,Fernando Herz (1) Mais... Palavra-chave Brazil (1) Cirrhosis (1) Disease burden (1) Epidemiology (1) HCV (1) HCV interferon (1) Hepatocellular carcinoma (1) Incidence (1) Sustained virologic response (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2015 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Disease burden of chronic hepatitis C in Brazil BJID Ferreira,Paulo Roberto Abrão; Brandão-Mello,Carlos Eduardo; Estes,Chris; Gonçales Júnior,Fernando Lopes; Coelho,Henrique Sérgio Moraes; Razavi,Homie; Cheinquer,Hugo; Wolff,Fernando Herz; Ferraz,Maria Lúcia Gomes; Pessoa,Mário Guimarães; Mendes-Correa,Maria Cássia. Background: Hepatitis C virus infection is a major cause of cirrhosis; hepatocellular carcinoma; and liver transplantation. The aim of this study was to estimate hepatitis C virus disease progression and the burden of disease from a nationwide perspective.Methods: Using a model developed to forecast hepatitis C virus disease progression and the number of cases at each stage of liver disease; hepatitis C virus-infected population and associated disease progression in Brazil were quantified. The impact of two different strategies was compared: higher sustained virological response and treatment eligibility rates (1) or higher diagnosis and treatment rates associated with increased sustained virological response rates (2).Results: The number of infected... Tipo: Info:eu-repo/semantics/article Palavras-chave: HCV; Disease burden; Epidemiology; Incidence; Brazil. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400363 Effect of sustained virologic response on the incidence of hepatocellular carcinoma in patients with HCV cirrhosis BJID Cheinquer,Nelson; Cheinquer,Hugo; Wolff,Fernando H; Coelho-Borges,Silvia. BACKGROUND AND OBJECTIVES: Evidence suggests that sustained virologic response to interferon treatment decreases incidence of hepatocellular carcinoma in patients with hepatitis C virus cirrhosis. This study was designed to compare the incidence of hepatocellular carcinoma among cirrhotic patients exposed to interferon based treatment with or without achieving a sustained virological response, in order to evaluate the role of interferon itself in the prevention hepatocellular carcinoma. METHODS: A cohort of 85 patients with compensated hepatitis C cirrhosis was followed after treatment with interferon and ribavirin. Sustained virological response was defined as negative polymerase chain reaction assay 24 weeks after the end of treatment. Patients were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatocellular carcinoma; HCV interferon; Sustained virologic response; Cirrhosis. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500006 Registros recuperados: 2 Primeira ... 1 ... Última

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