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Genomic variation and population structure detected by single nucleotide polymorphism arrays in Corriedale, Merino and Creole sheep Genet. Mol. Biol.
Grasso,Andrés N; Goldberg,Virginia; Navajas,Elly A; Iriarte,Wanda; Gimeno,Diego; Aguilar,Ignacio; Medrano,Juan F; Rincón,Gonzalo; Ciappesoni,Gabriel.
The aim of this study was to investigate the genetic diversity within and among three breeds of sheep: Corriedale, Merino and Creole. Sheep from the three breeds (Merino n = 110, Corriedale n = 108 and Creole n = 10) were genotyped using the Illumina Ovine SNP50 beadchip®. Genetic diversity was evaluated by comparing the minor allele frequency (MAF) among breeds. Population structure and genetic differentiation were assessed using STRUCTURE software, principal component analysis (PCA) and fixation index (F ST). Fixed markers (MAF = 0) that were different among breeds were identified as specific breed markers. Using a subset of 18,181 single nucleotide polymorphisms (SNPs), PCA and STUCTURE analysis were able to explain population stratification within...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Allele frequencies breed composition; Fixation index; Ovine SNP50; Population stratification; Principal component analysis.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000300011
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