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	Provedor de dados BJMBR (5) Autor Colombari,E. (5) Menani,J.V. (2) Blanch,G.T. (1) Callera,J.C. (1) Cardoso,L.M. (1) Chianca-Jr.,D.A. (1) Colombari,D.S.A. (1) De Luca Jr.,L.A. (1) Freiria-Oliveira,A.H. (1) Johnson,R.A. (1) Kozma,F. (1) Moraes,M.F.D. (1) Ogihara,C.A. (1) Pedrosa,M.L. (1) Sato,M.A. (1) Schoorlemmer,G.H.M. (1) Silva,M.E. (1) Mais... Palavra-chave Blood pressure (2) Nucleus of the solitary tract (2) Arterial pressure (1) Awake rats (1) Baroreflex (1) Bezold-Jarisch reflex (1) Carbon monoxide (1) Central nervous system (1) Commissural nucleus of the rat solitary tract (1) Deferoxamine (1) Furosemide (1) GABA receptors (1) Heart rate (1) Heme (1) Heme oxygenase (1) Hindbrain (1) Iron dextran (1) Iron overload (1) Isoproterenol (1) Muscimol (1) Mais... Tipo do documento Info:eu-repo/semantics/article (5) Ano 2009 (1) 2007 (1) 2005 (2) 1999 (1) País Brazil (5) Idioma Inglês (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Baroreflex function in conscious rats submitted to iron overload BJMBR Cardoso,L.M.; Pedrosa,M.L.; Silva,M.E.; Moraes,M.F.D.; Colombari,E.; Chianca-Jr.,D.A.. Our hypothesis is that iron accumulated in tissue, rather than in serum, may compromise cardiovascular control. Male Fischer 344 rats weighing 180 to 220 g were divided into 2 groups. In the serum iron overload group (SIO, N = 12), 20 mg elemental iron was injected ip daily for 7 days. In the tissue iron overload group (TIO, N = 19), a smaller amount of elemental iron was injected (10 mg, daily) for 5 days followed by a resting period of 7 days. Reflex heart rate responses were elicited by iv injections of either phenylephrine (0.5 to 5.0 µg/kg) or sodium nitroprusside (1.0 to 10.0 µg/kg). Baroreflex curves were determined and fitted to sigmoidal equations and the baroreflex gain coefficient was evaluated. To evaluate the role of other than a direct effect... Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreflex; Iron overload; Heart rate; Blood pressure; Iron dextran; Deferoxamine. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200008 Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions BJMBR Johnson,R.A.; Kozma,F.; Colombari,E.. Carbon monoxide (CO) is a pollutant commonly recognized for its toxicological attributes, including CNS and cardiovascular effects. But CO is also formed endogenously in mammalian tissues. Endogenously formed CO normally arises from heme degradation in a reaction catalyzed by heme oxygenase. While inhibitors of endogenous CO production can raise arterial pressure, heme loading can enhance CO production and lead to vasodepression. Both central and peripheral tissues possess heme oxygenases and generate CO from heme, but the inability of heme substrate to cross the blood brain barrier suggests the CNS heme-heme oxygenase-CO system may be independent of the periphery. In the CNS, CO apparently acts in the nucleus tractus solitarii (NTS) promoting changes in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Carbon monoxide; Heme; Heme oxygenase; Blood pressure; Central nervous system; Vascular tone. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100001 Changes in sodium appetite evoked by lesions of the commissural nucleus of the tractus solitarius BJMBR Ogihara,C.A.; Schoorlemmer,G.H.M.; Colombari,E.; Sato,M.A.. Ablation of the area postrema/caudal nucleus of the tractus solitarius (NTS) complex increases sodium intake, but the effect of selective lesions of the caudal NTS is not known. We measured depletion-induced sodium intake in rats with electrolytic lesions of the commissural NTS that spared the area postrema. One day after the lesion, rats were depleted of sodium with furosemide (10 mg/kg body weight, sc) and then had access to water and a sodium-deficient diet for 24 h when 1.8% NaCl was offered. Water and saline intakes were measured for 2 h. Saline intake was higher in lesioned than in sham-lesioned rats (mean ± SEM: 20 ± 2 vs 11 ± 3 mL/2 h, P < 0.05, N = 6-7). Saline intake remained elevated in lesioned rats when the tests were repeated 6 and 14 days... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nucleus of the solitary tract; Sodium appetite; Sucrose; Furosemide. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600014 Lesions of the commissural subnucleus of the nucleus of the solitary tract increase isoproterenol-induced water intake BJMBR Blanch,G.T.; Freiria-Oliveira,A.H.; Colombari,E.; Menani,J.V.; Colombari,D.S.A.. The nucleus of the solitary tract (NTS) is the primary site of the cardiovascular afferent information about arterial blood pressure and volume. The NTS projects to areas in the central nervous system involved in cardiovascular regulation and hydroelectrolyte balance, such as the anteroventral third ventricle region and the lateral parabrachial nucleus. The aim of the present study was to investigate the effects of electrolytic lesion of the commissural NTS on water and 0.3 M NaCl intake and the cardiovascular responses to subcutaneous injection of isoproterenol. Male Holtzman rats weighing 280 to 320 g were submitted to sham lesion or electrolytic lesion of the commissural NTS (N = 6-15/group). The sham-lesioned rats had the electrode placed along the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nucleus of the solitary tract; Commissural nucleus of the rat solitary tract; Water intake; Arterial pressure; Isoproterenol; Hindbrain. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800013 The bradycardic and hypotensive responses to serotonin are reduced by activation of GABA A receptors in the nucleus tractus solitarius of awake rats BJMBR Callera,J.C.; Colombari,E.; De Luca Jr.,L.A.; Menani,J.V.. We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 µg/rat) in awake male Holtzman rats. 5-HT was injected in rats with stainless steel cannulas implanted bilaterally in the NTS, before and 5, 15, and 60 min after bilateral injections of muscimol or baclofen into the NTS. The responses to 5-HT were tested before and after the injection of atropine methyl bromide. Muscimol (50 pmol/50 nl, N = 8) into the NTS increased basal mean arterial pressure (MAP) from 115 ± 4 to 144 ± 6 mmHg, did not change basal heart rate (HR) and reduced the bradycardia (-40 ± 14 and -73 ± 26... Tipo: Info:eu-repo/semantics/article Palavras-chave: Muscimol; GABA receptors; Nucleus tractus solitarius; Parasympathetic component; Bezold-Jarisch reflex; Awake rats. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700016 Registros recuperados: 5 Primeira ... 1 ... Última

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