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Chronic renal failure in equine due to ascending pyelonephritis predisposed by cauda equina syndrome: case report Arq. Bras. Med. Vet. Zootec.
Fonteque,J.H.; Granella,M.C.S.; Souza,A.F.; Mendes,R.P.; Schade,J.; Borelli,V.; Costa,A.; Costa,P.G..
ABSTRACT This report describes the case of a mare, of the Campeiro breed, used as an embryo donor, which had recurrent cystitis and urinary incontinence crisis. Clinical signs evolved to progressive weight loss, anorexia, apathy, and isolation from the group. Physical examination showed tail hypotonia, perineal hypalgesia, rectal and bladder sagging compatible with signs related to cauda equina syndrome. Complementary laboratory and sonographic assessment, and necropsy confirmed the diagnosis of chronic renal failure (CRF), which was attributed to the ascending pyelonephritis. The examination of urine culture showed growth of bacteria of the genus Streptococcus sp. This is a rare case in the equine species where the lower motor neuron dysfunction led the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Campeiro; Nephropathy; Neuropathy; Urinary tract.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000200347
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Gender-related differences in the effects of nitric oxide donors on neuroleptic-induced catalepsy in mice BJMBR
Pires,J.G.P.; Costa,P.G.; Saraiva,F.P.; Bonikovski,V.; Futuro Neto,H.A..
It has been suggested that nigrostriatal dopaminergic transmission is modulated by nitric oxide (NO). Since there is evidence that gonadal hormones can affect extrapyramidal motor behavior in mammals, we investigated the effects of isosorbide dinitrate (ISD), linsidomine (SIN-1) and S-nitroso-N-acetylpenicillamine (SNAP), three pharmacologically different NO donors, on neuroleptic-induced catalepsy in 60- to 80-day-old male and female albino mice. Catalepsy was induced with haloperidol (1 mg/kg, ip) and measured at 30-min intervals by means of a bar test. Drugs (or appropriate vehicle) were injected ip 30 min before haloperidol, with each animal being used only once. ISD (5, 20 and 50 mg/kg) caused a dose-dependent inhibition of catalepsy in male mice...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neuroleptic-induced catalepsy; Nitric oxide donors; Gender differences; Linsidomine; SNAP; Isosorbide dinitrate.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000200012
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