|
|
|
|
| |
|
|
Chiapello, H.; Bourgait, I.; Sourivong, F.; Heuclin, G.; Gendrault-Jacquemard, A.; Petit, M.A.; El Karoui, M.. |
Background :Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to address questions about bacterial genome evolution, a task that requires reliable fine comparison data of closely related genomes. Recent analyses have shown, using pairwise whole genome alignments, that it is possible to segment bacterial genomes into a common conserved backbone and strain-specific sequences called loops.Results :Here, we generalize this approach and propose a strategy that allows systematic and non-biased genome segmentation based on multiple genome alignments. Segmentation analyses, as applied to 13 different bacterial species, confirmed the feasibility of our... |
Tipo: Journal Article |
Palavras-chave: GENOME BACTERIEN; EVOLUTION DU GENOME; COMPARAISON DE GENOME ENTIER BACTERIAL GENOME; GENOME EVOLUTION. |
Ano: 2005 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007f72738ba&uri=/notices/prodinra1/2007/08/ |
| |
|
|
|