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A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep Inra
Clop, A.; Marcq, F.; Takeda, H.; Pirottin, D.; Tordoir, X.; Bibé, B.; Bouix, J.; Caimen, F.; Elsen, J.M.; Eychenne, F.; Larzul, C.; Laville, E.; Meish, F.; Milenkovic, D.; Tobin, J.; Charlier, C.; Georges, M..
Tipo: Journal Article Palavras-chave: TEXEL SHEEP; MYOSTATIN GENE; MUSCULARITY; HYPERTROPHY; GDF8; SNP.
Ano: 2006 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20087ed0d44b&uri=/notices/prodinra1/2008/09/
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Identification of new quantitative trait loci (other the the PRNP gene) modulating the scrapie incubation period in sheep Inra
Moreno-Romieux, C.; Cosseddu, G.M.; Schibler, L.; Roig, A.; Moazami-Goudarzi, K.; Andréoletti, O.; Eychenne, F.; Lajous, D.; Schelcher, F.; Cribiu, E.; Laurent, P.; Vaiman, D.; Elsen, J.M..
ABSTRACTAlthough susceptibility to scrapie is largely controlled by the PRNP gene, we have searched for additionalgenomic regions that affect scrapie incubation time in sheep, using two half-sib families with asusceptible PRNP genotype and naturally infected by scrapie. Quantitative trait loci were detected on OAR6 and OAR18.
Tipo: Journal Article Palavras-chave: RESISTANCE A LA TREMBLANTE; OVINS SCRAPIE RESISTANCE; QTL; SHEEP.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2008cdc7e0d5&uri=/notices/prodinra1/2008/06/
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Modelling the spread of scrapie in a sheep flock: evidence for increased transmission during lambing seasons Inra
Touzeau, S.; Chase-Topping, M.E.; Matthews, L.; Lajous, D.; Eychenne, F.; Hunter, N.; Foster, J.D.; Simm, G.; Elsen, J.M.; Woolhouse, M.E.J..
Presence of scrapie infectivity in the placenta suggests the possibility of increased transmission of scrapie during the lambing season. This hypothesis was explored here using a mathematical model of scrapie transmission dynamics which has previously been successfully used to study several scrapie outbreaks in Scottish sheep flocks. It was applied here to the Langlade experimental sheep flock (INRA Toulouse, France), in which a natural scrapie epidemic started in 1993. Extensive data were available, including pedigree, scrapie histopathological diagnoses and PrP genotypes. Detailed simulations of the scrapie outbreak reveal that the observed patterns of seasonality in incidence can not be accounted for by seasonality in demography alone and provide strong...
Tipo: Journal Article Palavras-chave: TREMBLANTE OVINE; TRANSMISSION INTRA TROUPEAU; SENSIBILITE GENETIQUE; SAISON; AGNELAGE SCRAPIE; EPIDEMIOLOGY; SHEEP; LAMBING SEASON.
Ano: 2006 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007add0f436&uri=/notices/prodinra1/2010/10/
Registros recuperados: 3
Primeira ... 1 ... Última
 

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