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| CURI, R. A.; KRAUSKOPF, M. K.; HADLICH, J. C.; FORTES, M. R. S.; VANKAN, D. M.; SILVA, J. A. V.; OLIVEIRA, H. N. de; MOTA, M. D. S. da. |
| The objective of this work was to evaluate the effects of single?nucleotide polymorphisms (SNPs) in the genes IGF1 (AF_017143.1:g.198C>T), MSTN (AF_320998.1:g.433C>A), MYOD1 (NC_007313:g.1274A>G) and MYF5 (NC_007303:g.1911A>G) on carcass and meat traits in Nelore (Bos indicus) and Nelore x B. taurus. A total of 300 animals were genotyped and phenotyped for rib eye area (REA), backfat thickness (BT), intramuscular fat (IF), shear force (SF) and myofibrillar fragmentation index (MFI). The effects of allele substitution for each SNP were estimated by regression of the evaluated phenotypes on the number of copies of a particular allele using the general linear model. The polymorphism at IGF1 was non?informative in Nelore animals. In crossbred... |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Maciez da carne; Gene candidato; Gado nelore; Carcaça; Zebu; Bos taurus; Meat quality. |
| Ano: 2012 |
URL: http://www.alice.cnptia.embrapa.br/handle/doc/931238 |
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| CURI, R. A.; FORTES, M. R. S.; CHARDULO, L. A. L.; SILVEIRA, A. C.; DE BENI ARRIGONE, M.; MARTINS, C. L.; ASSUMPÇÃO, M. E. O. d' A.; OLIVEIRA, H. N. de. |
| Abstract - The objective of this work was to estimate the allelic and genotypic frequencies of CAST/XmnI, a calpastatin gene polymorphism, and CAPN530, a calpain 1 large subunit gene polymorphism, in different beef genetic groups (Nelore and Nelore x Bos taurus), and to investigate associations between these polymorphisms and carcass and meat traits. Three hundred animals ? comprising 114 Nelore, 67 Angus x Nelore, 44 Rubia Gallega x Nelore, 41 Canchim, 19 Brangus three-way cross and 15 Braunvieh three-way cross ? were genotyped by PCR-RFLP and phenotyped for rib-eye area (REA), back-fat thickness (BT), intramuscular fat (IF), shear force (SF) and myofibrillar fragmentation index (MFI). The occurrence of the two alleles of the CAST/XmnI and CAPN530 single... |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Calpain gene; Calpastatin gene; Single nucleotide polymorphisms; Bos indicus; Meat tenderness. |
| Ano: 2009 |
URL: http://www.alice.cnptia.embrapa.br/handle/doc/662457 |
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| AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A.. |
| Mineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF... |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Expressão gênica; Bos Indicus; Gado Nelore; Cattle; Gene expression. |
| Ano: 2020 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1124802 |
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| AFONSO, J.; COUTINHO, L. L.; TIZIOTO, P. C.; DINIZ, W. J. da S.; LIMA, A. O. de; ROCHA, M. I. P.; BUSS, C, E.; ANDRADE, B. G. N. A.; PIAYA. O.; SILVA, J. V.; LINS, L. A.; GROMBONI, C. F.; NOGUEIRA, A. R. de A.; FORTES, M. R. S.; MOURÃO, G. B.; REGITANO, L. C. de A.. |
| Mineral content affects the biological processes underlying beef quality. Muscle mineral concentration depends not only on intake-outtake balance and muscle type, but also on age, environment, breed, and genetic factors. |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Muscle type; Mineral concentrations; Nelore; Beef quality; Beef cattle. |
| Ano: 2019 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1115486 |
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| KASARAPU, P.; PORTO NETO, L. R.; FORTES, M. R. S.; LEHNERT, S. A.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A.; GEORGE, A.; REVERTER, A.. |
| Numerical approaches to high-density single nucleotide polymorphism (SNP) data are often employed independently to address individual questions. We linked independent approaches in a bioinformatics pipeline for further insight. The pipeline driven by heterozygosity and Hardy-Weinberg equilibrium (HWE) analyses was applied to characterize Bos taurus and Bos indicus ancestry. We infer a gene co-heterozygosity network that regulates bovine fertility, from data on 18,363 cattle with genotypes for 729,068 SNP. Hierarchical clustering separated populations according to Bos taurus and Bos indicus ancestry. The weights of the first principal component were subjected to Normal mixture modelling allowing the estimation of a gene?s contribution to the Bos taurus-Bos... |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Hardy-Weinberg equilibrium; Bos Indicus; Bos Taurus. |
| Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1074938 |
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| KASARAPU, P.; PORTO-NETO, L. R.; FORTES, M. R. S.; LEHNERT, S. A.; MUDADU, M. de A.; COUTINHO, L.; REGITANO, L. C. de A.; GEORGE, A.; REVERTER, A.. |
| Numerical approaches to high-density single nucleotide polymorphism (SNP) data are often employed independently to address individual questions. We linked independent approaches in a bioinformatics pipeline for further insight. The pipeline driven by heterozygosity and Hardy-Weinberg equilibrium (HWE) analyses was applied to characterize Bos taurus and Bos indicus ancestry. We infer a gene co-heterozygosity network that regulates bovine fertility, from data on 18,363 cattle with genotypes for 729,068 SNP. Hierarchical clustering separated populations according to Bos taurus and Bos indicus ancestry. The weights of the first principal component were subjected to Normal mixture modelling allowing the estimation of a gene's contribution to the Bos taurus-Bos... |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Bioinformática; Polimorfismo de nucleotídeo único; Hardy-Weinberg equilibrium; Bos taurus; Bos indicus; Bioinformatics; Single nucleotide polymorphism. |
| Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1086886 |
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