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| Osório,L.G.; Silva,A.L.; Fonseca,A.O.S.; Dias,T.P.; Martins,O.A.; Faria,R.O.; Meireles,M.C.A.; Cleff,M.B.; Freitag,R.; Mello,J.R.B.. |
| RESUMO Aspergillus fumigatus, A. flavus e A. niger são os mais importantes agentes etiológicos da aspergilose, relevante micose aviária, com tratamento ineficaz e altas taxas de mortalidade. Em vista da importância da aspergilose, da necessidade de prospectar novos fármacos e do potencial terapêutico do óleo essencial de Origanum vulgare L. (OEO), o orégano, objetivou-se avaliar a sensibilidade in vitro de isolados clínicos de Aspergillus spp. em relação ao OEO. O óleo foi obtido por hidrodestilação em Clevenger, e a análise química realizada por cromatografia de massa (GC/MS). Observaram-se 15 diferentes compostos ativos, sendo 4-terpineol, hidrato de sabinene e timol os majoritários. Nos testes de microdiluição em caldo (Reference..., 2008), todos os... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Orégano; Atividade anti-Aspergillus; Lamiaceae; Antifungigrama. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100204 |
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| Peter,C.M.; Waller,S.B.; Picoli,T.; Osório,L.G.; Zani,J.L.; Meireles,M.C.A.; Faria,R.O.; Mello,J.R.B.; Hubner,S.O.; Lima,M.; Fischer,G.. |
| ABSTRACT In this study, we described the antifungal activity of three Brazilian propolis extracts: brown, green and from jataí bees against Sporothrix brasiliensis. The extracts were obtained from ethanolic extraction and their chemical composition was determined by high-performance liquid chromatography coupled to mass spectrometry. The cellular toxicity was measured in MDBK (Madin-Darby Bovine Kidney) cells and quantified by the MTT assay (3- (4,5 dimethylthiazol-2yl -2,5-diphenyl-2H bromine tetrazolato). For antifungal activity, the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were determined by broth microdilution. The results showed that cell toxicity was not observed at lower concentrations (0.097 to 0.39μg/ml)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Zoonosis; Itraconazole; Antifungal resistance; Therapeutic alternative. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300819 |
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| Osório,L.G.; Xavier,M.O.; Ladeira,S.R.L.; Silva Filho,R.P.; Faria,R.O.; Vargas,G.D'Á.; Cabana,A.L.; Mello,J.R.B.; Meireles,M.C.A.. |
| The bumblefoot or pododermatitis is among the diseases with the highest morbidity in Magellanic penguins, sometimes evolving to septicemia and death. Therefore, this study aimed to relate the main species involved in the disorder, as well as the in vitro susceptibility profile of the microorganisms against routine antimicrobial usage in Veterinary Medicine. During two years in vivo material was harvested from 200 footpads (n=100 animals) for microbiological analysis and in vitro susceptibility tests against the Antibiotic enrofloxacin, streptomycin, penicillin and cephalosporin. Bacteria have been identified both as part of permanent and transient microbiota, also being associated to 100% of the pododermatitis cases. The most prevalent genus were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pododermatitis; Magellanic penguins; Bacterial susceptibility. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000100008 |
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