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| Le Hesran, Jean-Yves; Boudin, Christian; Personne, P.; Devries, C.; Chambon, R.; Foumane, V.; Fievet, Nadine; Cot, Michel. |
| Since 1985, chloroquine resistance (CR) became evident in Cameroon, and rapidly spread out over the country. Despite such a situation, chloroquine is still the first antimalarial drug. CR follow up was mostly carried out by in vivo tests among schoolchildren. In this population, of a mean 9 yrs of age, a CR rate of 30 to 45% was reported. However, this may not show the true level of CR, because of the interaction of immunity in controlling parasite growth. Therefore, in southern Cameroon, we studied the activity of 25 mg/kg over 3 days of chloroquine and amodiaquine in treating asymptomatic children ranging from 1 to 15 yrs, with parasite density > 1000/microl. Following chloroquine treatment, children with treatment failure by D7 in the 0-2, 3-4, 5-9... |
| Tipo: Text |
Palavras-chave: PALUDISME; CHIMIOPROPHYLAXIE; TRAITEMENT MEDICAL; SENSIBILITE RESISTANCE; ENFANT; CHLOROQUINE; AMODIAQUINE. |
| Ano: 1996 |
URL: http://www.documentation.ird.fr/hor/fdi:010007004 |
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| Fievet, Nadine; Cot, Michel; Chougnet, C.; Maubert, B.; Bickii, J.; Dubois, B.; Le Hesran, Jean-Yves; Frobert, Y.; Migot, F.; Romain, F.; Verhave, J.P.; Louis, F.; Deloron, Philippe. |
| Tipo: Text |
Palavras-chave: PALUDISME; GROSSESSE; EPIDEMIOLOGIE; IMMUNITE; SEROLOGIE; ANTICORPS; ANTIGENE. |
| Ano: 1995 |
URL: http://www.documentation.ird.fr/hor/fdi:010004231 |
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