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Holth, T. F.; Eidsvoll, D. P.; Farmen, E.; Sanders, M. B.; Martinez-gomez, C.; Budzinski, H.; Burgeot, Thierry; Guilhermino, L.; Hylland, K.. |
The aim of this study was to characterise concentration- and time-dependent responses in juvenile Atlantic cod (Gadus morhua) following exposure for one and three weeks to the water-soluble fraction (WAF) of three weathered oils: Arabian Light crude oil (ALC), North Sea crude oil (NSC) and ship-diesel. The sum of polycyclic aromatic hydrocarbons (PAH) in water was highest after one week of exposure and within environmentally relevant concentrations. PAH metabolites in bile confirmed exposure to and uptake of PAHs. Hepatic cytochrome P450 1A (CYP1A) gene expression (here and later the phrase gene expression is used synonymously to gene transcription, although it is acknowledged that gene expression is also regulated by, e.g., translation and protein... |
Tipo: Text |
Palavras-chave: Atlantic cod; Biomarkers; Weathered crude oil; Ship-diesel; Water accommodated fraction; Time-course. |
Ano: 2014 |
URL: http://archimer.ifremer.fr/doc/00190/30131/28593.pdf |
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Law, R.; Hanke, Georg; Angelidis, Michael; Batty, J.; Bignert, A.; Dachs, J.; Davies, I.; Denga, Y.; Duffek, A.; Herut, B.; Hylland, K.; Lepom, Peter; Leonards, P.; Mehtonen, J.; Piha, Henna; Roose, J.; Tronczynski, Jacek; Velikova, V.; Vethaak, D.. |
The Marine Strategy Framework Directive (2008/56/EC) (MSFD) requires that the European Commission (by 15 July 2010) should lay down criteria and methodological standards to allow consistency in approach in evaluating the extent to which Good Environmental Status (GES) is being achieved. ICES and JRC were contracted to provide scientific support for the Commission in meeting this obligation. A total of 10 reports have been prepared relating to the descriptors of GES listed in Annex I of the Directive. Eight reports have been prepared by groups of independent experts coordinated by JRC and ICES in response to this contract. In addition, reports for two descriptors (Contaminants in fish and other seafood and Marine Litter) were written by expert groups... |
Tipo: Text |
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Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/00077/18847/16420.pdf |
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Kammann, U.; Akcha, Farida; Budzinski, H.; Burgeot, Thierry; Gubbins, M. J.; Lang, T.; Le Menach, K.; Vethaak, A. D.; Hylland, K.. |
Polycyclic aromatic hydrocarbons (PAH) are environmental contaminants that pose significant risk to health of fish. The International Workshop on Integrated Assessment of Contaminant Impacts on the North Sea (ICON) provided the framework to investigate biomarker responses as well as contaminant concentrations side by side in marine ecosystems. Concentrations of the main PAH metabolites 1-hydroxypyrene, 1-hydroxyphenanthren and 3-hydroxybenzo(a)pyrene were determined in bile by HPLC with fluorescence detection. Fish species under investigation were dab (Limanda limanda), flounder (Platichthys flesus) and haddock (Melanogrammus aeglefinus). A contamination gradient was demonstrated from the low contaminated waters of Iceland and off-shore regions of the... |
Tipo: Text |
Palavras-chave: PAH metabolite; Dab; Flounder; Haddock; Marine monitoring; Atlantic; North Sea. |
Ano: 2017 |
URL: http://archimer.ifremer.fr/doc/00317/42861/42288.pdf |
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