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	Provedor de dados BABT (1) Autor Abdelbaky,Nayira (1) Al-Rasheed,Nawal (1) Al-Rasheed,Nouf (1) Faddah,Laila (1) Ibrahim,Hanan (1) Mohamed,Azza M (1) Mais... Palavra-chave Cardiotoxicity (1) Carnosine (1) Melatonin (1) Titanium dioxide nanoparticles (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2015 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Role of Carnosine and Melatonin in Ameliorating Cardiotoxicity of Titanium Dioxide Nanoparticles in the Rats BABT Al-Rasheed,Nouf; Faddah,Laila; Ibrahim,Hanan; Mohamed,Azza M; Al-Rasheed,Nawal; Abdelbaky,Nayira. The aim of this work was to study the possible cardiotoxicity of two different doses of 50 nm nano titanium dioxide (n-TiO2) and the possible modulating effects of the use of two natural antioxidants carnosine and melatonin. The results showed that TiO2- NPs produced deleterious effects on rat cardiac tissue as confirmed by the increased levels of serum myoglobin, troponin-T and CK-MB. Increased levels of serum Inflammatory markers represented by the tumor necrosis factor alpha (TNF-α) and Interleukin-6 (IL-6) was also noticed. Caspase3 and IGg were elevated compared to the control group in a dose dependant manner. treatment of the rats with Carnosine or melatonin. along with TiO2- NPs administration significantly improved most of the elevated biochemical... Tipo: Info:eu-repo/semantics/article Palavras-chave: Titanium dioxide nanoparticles; Cardiotoxicity; Carnosine; Melatonin. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400577 Registros recuperados: 1 Primeira ... 1 ... Última

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