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Registros recuperados: 9
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Association of skeletal muscle transcripts with fatty acid content in Nellore cattle. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; POLETI, M. D.; ANDRADE, S. C. da S.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LANNA, D. P. D.; TULLIO, R. R.; NASSU, R. T.; KOLTES, J. E.; WATERS, E. F.; REECY, J. M.; COUTINHO, L. L..
2016
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Conjugated linoleic acid; Oleic acid; Differentially expressed genes.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1060623
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Co-expression networks reveal potential regulatory roles of miRNAs in fatty acid composition of nelore cattle. Repositório Alice
OLIVEIRA, P. S. N. de; COUTINHO, L. L.; CESAR, A. S. M.; DINIZ, W. J. da S.; SOUZA, M. de S.; ANDRADE, B. G.; KOLTES, J. E.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REECY, J. M.; REGITANO, L. C. de A..
Fatty acid (FA) content affects the sensorial and nutritional value of meat and plays a significant role in biological processes such as adipogenesis and immune response. It is well known that, in beef, the main FAs associated with these biological processes are oleic acid (C18:1 cis9, OA) and conjugated linoleic acid (CLA-c9t11), which may have beneficial effects on metabolic diseases such as type 2 diabetes and obesity. Here, we performed differential expression and co-expression analyses, weighted gene co-expression network analysis (WGCNA) and partial correlation with information theory (PCIT), to uncover the complex interactions between miRNAs and mRNAs expressed in skeletal muscle associated with FA content. miRNA and mRNA expression data were...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Ácido linoleico conjugado; Ácido oleico; Ácidos graxos; Genômica; Redes de co-expressão; Integrative genomics; MRNA; MiRNA; Bos Indicus; Gado de Corte; Beef cattle; Conjugated linoleic acid; Oleic acid.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1110820
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Differences in the skeletal muscle transcriptome profile associated with extreme values of fatty acids content. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; POLETI, M. D.; ANDRADE, S. C. da S.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; FELICIO, A. M.; NASCIMENTO, M. L. do; CHAVES, A. S.; LANNA, D. P. D.; TULLIO, R. R.; NASSU, R. T.; KOLTES, J. E.; WATERS, E. F.; MOURAO, G. B.; ZERLOTINI NETO, A.; REECY, J. M.; COUTINHO, L. L..
bitstream/item/153206/1/artigo5-Cesar-BMCGenomics-2016.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Bos Indicus; Human health; Lipids.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1060542
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Expression quantitative trait loci (eQTL) hotspot regions from whole genome analysis of Nellore steers. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; LANNA, D. P. D.; POLETI, M. D.; KOLTES, J. E.; REECY, J. M.; FRITZ-WATERS, E.; KRAMER, L.; GARRICK, D.; MUDADU, M. de A.; TULLIO, R. R.; COUTINHO, L. L..
2016
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gado de corte; Nelore; Gado nelore; Nellore.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1057056
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Gene co-expression analysis indicates potential pathways and regulators of beef tenderness in Nellore cattle. Repositório Alice
GONÇALVES, T. M.; REGITANO, L. C. de A.; KOLTES, J. E.; CESAR, A. S. M.; ANDRADE, S. C. da S.; MOURAO, G. B.; GASPARIN, G.; MOREIRA, G. C. M.; FRITZ-WATERS, E.; REECY, J. M.; COUTINHO, L. L..
Beef tenderness, a complex trait affected by many factors, is economically important to beef quality, industry, and consumer?s palatability. In this study, RNA-Seq was used in network analysis to better understand the biological processes that lead to differences in beef tenderness. Skeletal muscle transcriptional profiles from 24 Nellore steers, selected by extreme estimated breeding values (EBVs) for shear force after 14 days of aging, were analyzed and 22 differentially expressed transcripts were identified. Among these were genes encoding ribosomal proteins, glutathione transporter ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), and synaptotagmin IV (SYT4). Complementary co-expression analyses using Partial Correlation with Information...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Qualidade da carne; Maciez da carne; Carne; Gado de Corte; Beef; Beef cattle; Beef quality.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1106256
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Identification of putative regulatory regions and transcription factors associated with intramuscular fat content traits. Repositório Alice
CESAR, A. S. M.; REGITANO, L. C. de A.; REECY, J. M.; POLETI, M. D.; OLIVEIRA, P. S. N.; OLIVEIRA, G. B. de; MOREIRA, G. C. M.; MUDADU, M. de A.; TIZIOTO, P. L.; KOLTES, J. E.; Fritz-Waters, E.; KRAMER, L.; GARRICK, D.; BEIKI, H.; GEISTLINGER, L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; COUTINHO, L. L..
Background: Integration of high throughput DNA genotyping and RNA-sequencing data allows for the identification of genomic regions that control gene expression, known as expression quantitative trait loci (eQTL), on a whole genome scale. Intramuscular fat (IMF) content and carcass composition play important roles in metabolic and physiological processes in mammals because they influence insulin sensitivity and consequently prevalence of metabolic diseases such as obesity and type 2 diabetes. However, limited information is available on the genetic variants and mechanisms associated with IMF deposition in mammals. Thus, our hypothesis was that eQTL analyses could identify putative regulatory regions and transcription factors (TFs) associated with...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Expressão gênica; EQTL; Ácidos graxos; Doenças metabólicas; Expression quantitative trait loci; Gene expression; Fatty acids; Mammals; Metabolic diseases.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1102203
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Liver DNA methylation profile in Nelore cattle extremes for feed efficiency. Repositório Alice
ROCHA, M. I. P.; SOUZA, M. M. de; DINIZ, W. J. S.; LIMA, A. O. de; AFONSO, J.; TIZIOTO, P. C.; OLIVEIRA, P. N. de; REGITANO, L. C. de A.; KOLTES, J. E.; NICIURA, S. C. M..
The production cost of cattle is high, especially the fraction related to animal nutrition. The increase in feed efficiency may provide increased efficiency in beef production, minimizing feed expenditures, methane gas emission and nitrogen excretion.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Feed efficiency; RRBS; Differential methylation; Beef production; Gado de Corte; Bovino; Gene expression regulation; Animal nutrition.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1110134
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Potential biomarkers for feed efficiency-related traits in nelore cattle identified by co-expression network and integrative genomics analyses. Repositório Alice
LIMA, A. O. de; KOLTES, J. E.; DINIZ, W. J. S.; OLIVEIRA, P. S. N. de; CESAR, A. S. M.; TIZIOTO, P. L.; AFONSO, J.; SOUZA, M. de S.; PETRINI, J.; ROCHA, M. I. P.; CARDOSO, T. F.; ZERLOTINI NETO, A.; COUTINHO, L. L.; MOURÃO, G. B.; REGITANO, L. C. de A..
Feed efficiency helps to reduce environmental impacts from livestock production, improving beef cattle profitability. We identified potential biomarkers (hub genes) for feed efficiency, by applying co-expression analysis in Longissimus thoracis RNA-Seq data from 180 Nelore steers. Six co-expression modules were associated with six feed efficiency-related traits (p-value ≤ 0.05). Within these modules, 391 hub genes were enriched for pathways as protein synthesis, muscle growth, and immune response. Trait-associated transcription factors (TFs) ELF1, ELK3, ETS1, FLI1, and TCF4, were identified with binding sites in at least one hub gene. Gene expression of CCDC80, FBLN5, SERPINF1, and OGN was associated with multiple feed efficiency-related traits...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Longissimus thoracis; Biomarcadores; Expressão gênica; Feed efficiency; Hub genes; Systems biology; WGCNA; Bos Indicus; Gene expression.
Ano: 2020 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1124356
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The structure of microbial populations in Nelore GIT reveals inter-dependency of methanogens in feces and rumen. Repositório Alice
ANDRADE, B. G. N.; DONATONI, F. A. B.; CUADRAT, R. R. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; MOURÃO, G. B.; COUTINHO, L. L.; REECY, J. M.; KOLTES, J. E.; WALSH, P.; BERNDT, A.; PALHARES, J. C. P.; REGITANO, L. C. de A..
The success of different species of ruminants in the colonization of a diverse range of environments is due to their ability to digest and absorb nutrients from cellulose, a complex polysaccharide found in leaves and grass. Ruminants rely on a complex and diverse microbial community, or microbiota, in a unique compartment known as the rumen to break down this polysaccharide. Changes in microbial populations of the rumen can affect the host?s development, health, and productivity. However, accessing the rumen is stressful for the animal. Therefore, the development and use of alternative sampling methods are needed if this technique is to be routinely used in cattle breeding. To this end, we tested if the fecal microbiome could be used as a proxy for the...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Microbiota; Metabarcoding; Bactéria; Bos Indicus; Gado Nelore; Archaea; Methanobrevibacter; Microbiome.
Ano: 2020 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1121594
Registros recuperados: 9
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