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LEAL, L. K. A. M.; PIERDONÁ, T. M.; GÓES, J. G. S.; CANUTO, K. M.; SILVEIRA, E. R.; BEZERRA, A. M. E.; VIANA, G. S. B.. |
The objectives of this work were to carry out a comparative chemical study and to evaluate the antinociceptive and anti-inflammatory activities of ethanol extracts (EtOHE) and vanilic acid (VA) from cultivated and wild Amburana cearensis A.C. Smith (Fabaceae), an endangered species used in Northeast Brazil for the treatment of asthma. The HPLC analysis of EtOHE, showed that coumarin (CM) and VA were the major constituents from the cultivated plant, while in the extract from the wild plant the major constituents were amburoside A (AMB) and CM. Pharmacological tests were performed with male Swiss mice or male Wistar rats acutely administered with 100?400 mg/kg, p.o. of EtOHEs or 12.5?50 mg/kg, p.o. of VA. EtOHEs from A. cearensis with 4, 7 or 9 months of... |
Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Amburana cearensis; Vanillic acid; HPLC; Antinociceptive activity; Anti-inflammatory activity. |
Ano: 2011 |
URL: http://www.alice.cnptia.embrapa.br/handle/doc/904909 |
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MORAES, A. F.; MOREIRA FILHO, R. N. F.; PASSOS, C. C. O.; CUNHA, A. P.; SILVA, L. M. A. e; FREITAS, L. B. N.; VASCONCELOS, N. F.; RICARDO, N. M. P. S.; CANUTO, K. M.; ROSA, M. de F.; LEAL, L. K. A. M.; VIEIRA, R. S.. |
bitstream/item/197850/1/ART19014.pdf |
Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Filmes anticoagulantes; Hemocompatibilidade; Quitosana sulfatada; Sulfato. |
Ano: 2019 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1109287 |
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LEAL, L. K. A. M.; FONSECA, F. N.; PEREIRA, F. A.; CANUTO, K. M.; FELIPE, C. F. B.; FONTENELE, J. B.; PITOMBEIRA, M. V.; SILVEIRA, E. R.; VIANA, G. S. B.. |
The aim of this study was to investigate the possible beneficial effects of amburoside A, AMB [4-(0-b-d-glycopyranosyl) benzyl protocatechoate], against carbon tetrachloride (CCl) toxicity in rats. |
Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Amburana cearensis; AMB; Tratamento respiratório; Planta medicinal; Medicinal plant. |
Ano: 2008 |
URL: http://www.alice.cnptia.embrapa.br/handle/doc/161853 |
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