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	Provedor de dados BJMBR (3) Autor Leite,K.R.M. (3) Babeto,E. (1) Borim,A.A. (1) Camara-Lopes,L.H. (1) Coelho,A.M.M. (1) Duarte,M.C. (1) Machado,M.C.C. (1) Miyazaki,K. (1) Nesralhah,L.J. (1) Oliveira,V.L.L. (1) Pinotti,H.W. (1) Rahal,P. (1) Sampietre,S.N. (1) Silva,A.E. (1) Srougi,M. (1) Mais... Palavra-chave Acute pancreatitis (1) Gastric cancer (1) Gastric ulcer (1) Gene expression (1) Hepatic lesion (1) Intestinal metaplasia (1) Mitochondria (1) P53 (1) PCNA (1) Proliferating cell nuclear antigen (1) Prostate carcinoma (1) Protein expression (1) TERT (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2011 (1) 1999 (1) 1997 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Analysis of p53 expression and proliferative assessment using PCNA in localized prostate carcinoma BJMBR Leite,K.R.M.; Srougi,M.; Nesralhah,L.J.; Camara-Lopes,L.H.. The surgical specimens from 51 men submitted to radical prostatectomy for localized prostate cancer were examined by immunohistochemistry using proliferation cell nuclear antigen (PCNA) monoclonal antibody to evaluate the proliferative index (PI). The relationship between PI, biological variables and p53 protein expression was evaluated by immunohistochemistry. PI was low in invasive localized prostate carcinoma (mean, 12.4%) and the incidence of PCNA-positive cells was significantly higher in tumors with p53 expression (P = 0.0226). There was no statistical difference in PCNA values when biological parameters such as Gleason score, tumor volume, extraprostatic involvement, seminal vesicle infiltration or lymph node metastasis were considered. We conclude... Tipo: Info:eu-repo/semantics/article Palavras-chave: Prostate carcinoma; P53; Proliferating cell nuclear antigen; PCNA. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000300006 Expression of TERT in precancerous gastric lesions compared to gastric cancer BJMBR Duarte,M.C.; Babeto,E.; Leite,K.R.M.; Miyazaki,K.; Borim,A.A.; Rahal,P.; Silva,A.E.. The objective of this study was to determine the levels of TERT mRNA and TERT protein expression in stomach precancerous lesions such as intestinal metaplasia (IM) and gastric ulcer (GU) and compare them to gastric cancer (GC). Real-time PCR was performed to detect TERT mRNA expression levels in 35 biopsies of IM, 30 of GU, and 22 of GC and their respective normal mucosas. TERT protein was detected by immunohistochemistry in 68 samples, 34 of IM, 23 of GU, and 11 of GC. Increased TERT mRNA expression levels were observed in a significant number of cases, i.e., 46% of IM, 50% of GU, and 79% of GC. The relative mean level of TERT mRNA after normalization with the β-actin reference gene and comparison with the respective adjacent normal mucosa was slightly... Tipo: Info:eu-repo/semantics/other Palavras-chave: Gastric ulcer; Intestinal metaplasia; Gastric cancer; TERT; Gene expression; Protein expression. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000200003 Hepatic damage during acute pancreatitis in the rat BJMBR Coelho,A.M.M.; Machado,M.C.C.; Sampietre,S.N.; Leite,K.R.M.; Oliveira,V.L.L.; Pinotti,H.W.. We studied the alterations in the metabolism of liver mitochondria in rats with acute pancreatitis. Male Wistar rats were allocated to a control group (group I) and to five other groups corresponding to 2, 4, 12, 24 and 48 h after the induction of acute pancreatitis by the injection of 5% sodium taurocholate into the pancreatic duct. Sham-operated animals were submitted to the same surgical steps except for the induction of acute pancreatitis. Mitochondrial oxidation and phosphorylation were measured polarographically by determining oxygen consumption without ADP (basal respiration, state 4) and in the presence of ADP (activated respiration, state 3). Serum amylase, transaminases (ALT and AST) and protein were also determined. Ascitic fluid, contents of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute pancreatitis; Hepatic lesion; Mitochondria. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800006 Registros recuperados: 3 Primeira ... 1 ... Última

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