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Histidine-tryptophan-ketoglutarate solution decreases mortality and morbidity in high-risk patients with severe pulmonary arterial hypertension associated with complex congenital heart disease: an 11-year experience from a single institution 56
Li,X.W.; Lin,Y.Z.; Lin,H.; Huang,J.B.; Tang,X.M.; Long,X.M.; Lu,W.J.; Wen,Z.K.; Liang,J.; Li,D.Y.; Zhao,X.F..
Cardioplegic reperfusion during a long term ischemic period interrupts cardiac surgery and also increases cellular edema due to repeated solution administration. We reviewed the clinical experiences on myocardial protection of a single perfusion with histidine-tryptophan-ketoglutarate (HTK) for high-risk patients with severe pulmonary arterial hypertension associated with complex congenital heart disease. This retrospective study included 101 high-risk patients undergoing arterial switch operation between March 2001 and July 2012. We divided the cohort into two groups: HTK group, myocardial protection was carried out with one single perfusion with HTK solution; and St group, myocardial protection with conventional St. Thomas' crystalloid cardioplegic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Histidine-tryptophan-ketoglutarate; Myocardial protection; Cardiac surgery.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600703
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