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Susceptibility variation of Malassezia pachydermatis to antifungal agents according to isolate source BJM
Weiler,Caroline Borges; Jesus,Francielli Pantella Kunz de; Nardi,Graziela Habib; Loreto,Érico Silva; Santurio,Janio Morais; Coutinho,Selene Dall'Acqua; Alves,Sydney Hartz.
Malassezia pachydermatisis associated with dermatomycoses and otomycosis in dogs and cats. This study compared the susceptibility of M. pachydermatis isolates from sick (G1) and healthy (G2) animals to azole and polyene antifungals using the M27-A3 protocol. Isolates from G1 animals were less sensitive to amphotericin B, nystatin, fluconazole, clotrimazole and miconazole.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Malassezia pachydermatis; Susceptibility; Antifungal agents.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100026
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Synergistic effects of tacrolimus and azole antifungal compounds in fluconazole-susceptible and fluconazole-resistant Candida glabrata isolates BJM
Denardi,Laura Bedin; Mario,Débora Alves Nunes; Loreto,Érico Silva; Santurio,Janio Morais; Alves,Sydney Hartz.
In vitro interaction between tacrolimus (FK506) and four azoles (fluconazole, ketoconazole, itraconazole and voriconazole) against thirty clinical isolates of both fluconazole susceptible and -resistant Candida glabrata were evaluated by the checkerboard microdilution method. Synergistic, indifferent or antagonism interactions were found for combinations of the antifungal agents and FK506. A larger synergistic effect was observed for the combinations of FK506 with itraconazole and voriconazole (43%), followed by that of the combination with ketoconazole (37%), against fluconazole-susceptible isolates. For fluconazole-resistant C. glabrata, a higher synergistic effect was obtained from FK506 combined with ketoconazole (77%), itraconazole (73%), voriconazole...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida glabrata; Azole resistance; FK506; Combination therapy.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100125
Registros recuperados: 2
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