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Identification and characterization of microRNAs expressed in chicken skeletal muscle. Repositório Alice
ANDREOTE, A. P. D.; ROSÁRIO, M. F. do; LEDUR, M. C.; JORGE, E. C.; SONSTEGARD, T. S.; MATUKUMALLI, L.; COUTINHO, L. L..
MicroRNAs (miRNAs, miRs) encompass a class of small non-coding RNAs that often negatively regulate gene expression. miRNAs play an essential role in skeletal muscle, determining the proper development and maintenance of this tissue. In comparison to other organs and tissues, the full set of muscle miRNAs and its expression patterns are still poorly understood. In this report, a chicken skeletal muscle miRNA library was constructed, and the expression of selected miRNAs was further characterized during muscle development in chicken lines with distinct muscling phenotypes. Clone library sequence analysis revealed 40 small RNAs with similarities to previously described chicken miRNAs, seven miRNAs that were never identified before in chicken, and some...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Genetica animal; Galinha; Chickens; Molecular genetics; Cell proliferation.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1012924
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