|
|
|
| Registros recuperados: 20 | |
|
|
| MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L.. |
| Tipo: Separatas |
Palavras-chave: Re sequencing; Polymorphisms.; Abdominal fat.. |
| Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1032943 |
| |
|
|
| MARCHESI, J. A. P.; ONO, R. K.; CANTAO, M. E.; IBELLI, A. M. G.; PEIXOTO, J. de O.; MOREIRA, G. C. M.; GODOY, T. F.; COUTINHO, L. L.; MUNARI, D. P.; LEDUR, M. C.. |
| Abstract: Chicken feed efficiency (FE) traits are the most important economic traits in broiler production. Several studies evaluating genetic factors affecting food consumption in chickens are available. However, most of these studies identified genomic regions containing putative quantitative trait loci for each trait separately. It is still a challenge to find common gene networks related to these traits. Therefore, here, a genome-wide association study (GWAS) was conducted to explore candidate genomic regions responsible for Feed Intake (FI), Body Weight Gain (BWG) and Feed Conversion Ratio (FCR) traits and their gene networks. A total of 1430 broilers from an experimental population was genotyped with the high density Affymetrix 600K SNP array. A... |
| Tipo: Artigo de periódico |
Palavras-chave: Produção Animal; Genética Animal; Frango de Corte; Ganho de Peso; Genoma. |
| Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1133426 |
| |
|
|
| GONÇALVES, T. M.; REGITANO, L. C. de A.; KOLTES, J. E.; CESAR, A. S. M.; ANDRADE, S. C. da S.; MOURAO, G. B.; GASPARIN, G.; MOREIRA, G. C. M.; FRITZ-WATERS, E.; REECY, J. M.; COUTINHO, L. L.. |
| Beef tenderness, a complex trait affected by many factors, is economically important to beef quality, industry, and consumer?s palatability. In this study, RNA-Seq was used in network analysis to better understand the biological processes that lead to differences in beef tenderness. Skeletal muscle transcriptional profiles from 24 Nellore steers, selected by extreme estimated breeding values (EBVs) for shear force after 14 days of aging, were analyzed and 22 differentially expressed transcripts were identified. Among these were genes encoding ribosomal proteins, glutathione transporter ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), and synaptotagmin IV (SYT4). Complementary co-expression analyses using Partial Correlation with Information... |
| Tipo: Artigo de periódico |
Palavras-chave: Qualidade da carne; Maciez da carne; Carne; Gado de Corte; Beef; Beef cattle; Beef quality. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1106256 |
| |
|
| |
|
|
| ONO, R. K.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; SOLLERO, B. P.; SUREK, D.; MOREIRA, G. C. M.; GODOY, T. F.; COUTINHO, L. L.; LEDUR, M. C.. |
| Abstract: Due to the intense selection for heavier and faster growing broilers, metabolic disorders such as skeletal problems became a worldwide concern. Advances in genome-wide association study (GWAS) methodologies increased the possibility of elucidating the genetic architecture controlling bone integrity traits. Therefore, the aim of this study was to perform a GWAS to identify potential genetic markers and candidate genes associated with femur traits in a paternal broiler line developed by Embrapa. To this, three femur bone-related traits were evaluated in 1,433 chickens: dry matter (FDM), ash content (FAC) and breaking strength (FBS). Chickens were genotyped using the 600K Affymetrix® Axiom® HD panel. A total of 16 regions associated to FAC, being a... |
| Tipo: Separatas |
Palavras-chave: Integridade óssea; Características do fêmur; Associação genômica; QTLs; Melhoramento Genético Animal; Frango de Corte; Formação Óssea; Fêmur; Animal genetic resources; Broiler chickens; Bone metabolism; Quantitative trait loci. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1093205 |
| |
|
|
| BOSCHIERO, C.; MOREIRA, G. C. M.; GHEYAS, A.; GODOY, T. F.; GASPARIN, G.; MARIANI, P. D. S. C.; PADUAN, M.; COUTINHO, L. L.; CESAR, A. S. M.; LEDUR, M. C.. |
| Abstract: Background Meat and egg-type chickens have been selected for several generations for different traits. Artificial and natural selection for different phenotypes can change frequency of genetic variants, leaving particular genomic footprints throghtout the genome. Thus, the aims of this study were to sequence 28 chickens from two Brazilian lines (meat and white egg-type) and use this information to characterize genome-wide genetic variations, identify putative regions under selection using Fst method, and find putative pathways under selection. |
| Tipo: Artigo de periódico |
Palavras-chave: Fat deposition; Genetic variants; Next generation sequencing; Genoma; Frango de Corte; Linhagem; Ovo; Melhoramento Genético Animal; Polimorfismo Genético; Single nucleotide polymorphism; Egg industry; Broiler chickens; Genome; Poultry carcasses. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1091368 |
| |
|
|
| FERNANDES, A. C.; SILVA, V. H. da; GOES, C. P.; MOREIRA, G. C. M.; GODOY, T. F.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; LEDUR, M. C.; REZENDE, F. M. de; COUTINHO, L. L.. |
| Abstract Background: Copy number variations (CNVs) are a major type of structural genomic variants that underlie genetic architecture and phenotypic variation of complex traits, not only in humans, but also in livestock animals. We identified CNVs along the chicken genome and analyzed their association with performance traits. Genome-wide CNVs were inferred from Affymetrix® high density SNP-chip data for a broiler population. CNVs were concatenated into segments and association analyses were performed with linear mixed models considering a genomic relationship matrix, for birth weight, body weight at 21, 35, 41 and 42 days, feed intake from 35 to 41 days, feed conversion ratio from 35 to 41 days and, body weight gain from 35 to 41 days of age. Results: We... |
| Tipo: Artigo de periódico |
Palavras-chave: GWAS; CNVs; Copy number variations; QTLs; QPCR; Desempenho zootécnico; Genética Animal; Gallus Domesticus; Performance; Animal genetics; Genome-wide association study; Animal performance; Quantitative trait loci; Quantitative polymerase chain reaction; Gallus gallus. |
| Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1133197 |
| |
|
| |
|
| |
|
| |
|
|
| CESAR, A. S. M.; REGITANO, L. C. de A.; REECY, J. M.; POLETI, M. D.; OLIVEIRA, P. S. N.; OLIVEIRA, G. B. de; MOREIRA, G. C. M.; MUDADU, M. de A.; TIZIOTO, P. L.; KOLTES, J. E.; Fritz-Waters, E.; KRAMER, L.; GARRICK, D.; BEIKI, H.; GEISTLINGER, L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; COUTINHO, L. L.. |
| Background: Integration of high throughput DNA genotyping and RNA-sequencing data allows for the identification of genomic regions that control gene expression, known as expression quantitative trait loci (eQTL), on a whole genome scale. Intramuscular fat (IMF) content and carcass composition play important roles in metabolic and physiological processes in mammals because they influence insulin sensitivity and consequently prevalence of metabolic diseases such as obesity and type 2 diabetes. However, limited information is available on the genetic variants and mechanisms associated with IMF deposition in mammals. Thus, our hypothesis was that eQTL analyses could identify putative regulatory regions and transcription factors (TFs) associated with... |
| Tipo: Artigo de periódico |
Palavras-chave: Expressão gênica; EQTL; Ácidos graxos; Doenças metabólicas; Expression quantitative trait loci; Gene expression; Fatty acids; Mammals; Metabolic diseases. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1102203 |
| |
|
| |
|
|
| MOREIRA, G. C. M.; GODOY, T. F.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; LEDUR, M. C.; GARRICK, D.; SILVA, V. H. da; CROOIJAMANS, R. P.; GROENEN, M. A. M.; COUTINHO, L. L.. |
| Abstract: Carcass fat content is an economically important trait in commercial chickens. The use of genome-wide high density SNPs may improve the power and resolution to identify QTLs, putative candidate genes and copy number variations (CNVs), for selection programs. The main goal of this study was to identify genomic windows and putative candidate genes for carcass fat content. We checked the overlap of QTL with regions demonstrating signatures of selection and inherited CNVs identified in the same population. A total of 497 42 day-old chickens from the EMBRAPA F2 Chicken Resource Population developed for QTL studies were genotyped with the 600K SNP genotyping array (Affymetrix®), and phenotyped for carcass fat content weight (CFCW) and carcass fat... |
| Tipo: Separatas |
Palavras-chave: Genotyping by sequencing; Analyses were performed with GenSel; Selection signatures; 600k snp genotyping array; Melhoramento Genético Animal; Polimorfismo Genético; Frango de Corte; Carcaça; Gordura; Genoma; Animal genetic resources; Broiler chickens; Carcass characteristics; Abdominal fat; Genetic polymorphism; Single nucleotide polymorphism. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1093261 |
| |
|
| |
|
|
| KAPPELER, B. I. G.; REGITANO, L. C. de A.; POLETI, M. D.; CESAR, A. S. M.; MOREIRA, G. C. M.; GASPARIN, G.; COUTINHO, L. L.. |
| MicroRNAs (miRNAs) are small noncoding RNAs of approximately 22 nucleotides, highly conserved among species, which modulate gene expression by cleaving messenger RNA target or inhibiting translation. MiRNAs are involved in the regulation of many processes including cell proliferation, differentiation, neurogenesis, angiogenesis, and apoptosis. Beef tenderness is an organoleptic characteristic of great influence in the acceptance of meat by consumers. Previous studies have shown that collagen level, marbling, apoptosis and proteolysis are among the many factors that affect beef tenderness. Considering that miRNAs can modulate gene expression, this study was designed to identify differentially expressed miRNAs that could be modulating biological processes... |
| Tipo: Artigo de periódico |
Palavras-chave: Qualidade da carne; Bta-miR; Shear force; Gado de Corte; Carne; Bos Indicus; Beef cattle; Beef; Beef quality; MicroRNA. |
| Ano: 2019 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1106070 |
| |
|
|
| DEFANT, H.; MEIRA, A. N.; COUTINHO, L. L.; REGITANO, L. C. de A.; POLETI, M. D.; MOREIRA, G. C. M.; PADUAN, M.; MARIANI, P.; ZERLOTINI NETO, A.; MOURÃO, G. B.; CESAR, A. S. M.. |
| ABSTRACT. Genetic variations in genes involved in lipid storage, which also may interfere with important phenotypic traits such as intramuscular fat deposition in cattle, can represent useful markers in marker assisted selection programs. An important candidate gene is perilipin 2 (PLIN2) that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid droplets in different tissues including muscle. As reported by our group, PLIN2 expression level was associated with trans-eQTL (expression quantitative loci distant of gene associated) at chr3: 87, 253, 086 in Nellore cattle, where animals with different genotypes showed different expression level of PLIN2 among the 193 animals and the co-expression analysis... |
| Tipo: Artigo de periódico |
Palavras-chave: Perilipin 2; PLIN2; Polimorfismo de nucleotídeo único; SNP; Processos biológicos; Gordura intramuscular; Gota lipídica; Expressão gênica; Biological process; Lipid droplet; Variants; Gado; Bos Indicus; Nellore; Cattle; Single nucleotide polymorphism; Gene expression; Intramuscular fat. |
| Ano: 2019 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1119464 |
| |
|
| |
|
|
| BOSCHIERO, C.; GODOY, T. F.; MOREIRA, G. C. M.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L.. |
| Tipo: Separatas |
Palavras-chave: Chicken; SNP.; Breast muscle.. |
| Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1032831 |
| |
|
|
| BOSCHIERO, C.; GHEYAS, A.; GODOY, T. F.; MOREIRA, G. C. M.; GRADE, C. V. C.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. da S.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L.. |
| Tipo: Separatas |
Palavras-chave: Genômica; SNPs; Genomic analysis.; Galinha; Chickens.. |
| Ano: 2013 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/971388 |
| |
| Registros recuperados: 20 | |
|
|
|
