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Allele specific expression analysis in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; ZERLOTINI, A.; REGITANO, L. C..
2015
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Allele; Specific expression analysis; Bovine muscle tissue.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1029313
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Allele specific expression analysis in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; ZERLOTINI NETO, A.; REGITANO, L. C..
Imprinted genes have been target of many studies, mainly in human and mouse, and lately in bovines due to the interest of understanding the epigenetic mechanisms underlying important meat quality phenotypes and the possibility of applying it in animal breeding programs in the future. Genomic DNA from 146 steers was genotyped using the Illumina BovineHD BeadChip in order to identify heterozygous individuals with known allele origin.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioinformática; Expressão gênica; Genoma; Bioinformatics; Gene expression; Genome.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1035220
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Allele specific expression analysis in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; MOKRY, F. C.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A.; CESAR, A. S. M.; MORÉ, D.; MOURÃO, G.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; ZERLOTINI, A.; REGITANO, L. C..
Imprinted genes have been target of many studies, mainly in human and mouse, and lately in bovines due to the interest of understanding the epigenetic mechanisms underlying important meat quality phenotypes and the possibility of applying it in animal breeding programs in the future. Genomic DNA from 146 steers was genotyped using the Illumina BovineHD BeadChip in order to identify heterozygous individuals with known allele origin.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioinformática; Expressão gênica; Genoma; Bioinformatics; Genome; Gene expression.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1035029
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An insight into the linkage disequilibrium map of the Canchim beef cattle breed. Repositório Alice
MOKRY, F. B.; LIMA, A. O. de; MUDADU, M. A.; HIGA, R. H.; MEIRELLES, S. L. C.; REGITANO, L. C. de A..
The development of linkage disequilibrium (LD) maps is very important for understanding the nature of non-linear association between phenotypes and genes, as LD can be defined as the non-random segregation of a pair of alleles at polymorphic sites. Canchim is a composite beef cattle breed which was developed in the 1960's by the crossing of Bos indicus (3/8) x Charolais (5/8) animals. The objective in this study was to analyze the extension of LD maps from a Canchim beef cattle population.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Desequilíbrio de ligação; Gado; Linkage disequilibrium; Cattle; Zebu; Haplotypes.
Ano: 2012 URL: http://www.alice.cnptia.embrapa.br/handle/doc/946432
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Complex pattern of CAST allelic expression in bovine muscle tissue. Repositório Alice
SOUZA, M. M.; ZERLOTINI, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A. L.; MOKRY, F. B.; CESAR, A. S. M.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. A..
2014
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioinformática; Polimorfismo de nucleotídeo único; Bioinformatics; Single nucleotide polymorphism.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1007540
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Descriptive analysis of haplotypes in a population of Canchim beef cattle. Repositório Alice
MOKRY, F. B.; LIMA, A. O.; MUDADU, M. A.; HIGA, R. H.; MEIRELLES, S. L. C.; SILVA, M. V. B.; CARDOSO, F. F.; NICIURA, S. C. M.; ALENCAR, M. M.; REGITANO, L. C. A..
The aim in this study was to descriptively analyze haplotypes from a Canchim beef cattle population.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Desequilíbrio de ligação; Gado; Cattle; Linkage disequilibrium; Single nucleotide polymorphism.
Ano: 2012 URL: http://www.alice.cnptia.embrapa.br/handle/doc/946423
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Descriptive analysis of haplotypes in a population of Canchim beef cattle. Repositório Alice
MOKRY, F. B.; LIMA, A. O.; MUDADU, M. A.; HIGA, R. H.; MEIRELLES, S. L. C.; SILVA, M. V. B.; CARDOSO, F. F.; NICIURA, S. C. M.; ALENCAR, M. M.; REGITANO, L. C. A..
The aim in this study was to descriptively analyze haplotypes from a Canchim beef cattle population.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Desequilíbrio de ligação; Gado; Cattle; Linkage disequilibrium; Single nucleotide polymorphism.
Ano: 2012 URL: http://www.alice.cnptia.embrapa.br/handle/doc/967077
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Genetics mechanisms of resistance and response to tick infestation in Hereford cattle: a global view. Repositório Alice
MORÉ, D. D.; MALAGO JUNIOR, W.; MUDADU, M. A.; ZERLOTINI NETO, A.; GULIAS-GOMES, C. C.; IBELLI, A. M. G.; CATOIA, V.; CARDOSO, F. F.; REGITANO, L. C. A..
The present study aims to analyze the bovine skin transcriptome before and after tick infestation between resistant and susceptible cattle, to identify genes differentially expressed (DE), SNPs in transcribed (QTLs) and regulatory (eQTLs) regions, alternative transcription sites and imprinted genes to draw a map of the skin transcriptome in response to tick infestation.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gado; Genética; Infestação de carrapatos; Cattle; Genetics; Tick infestations.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/980594
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Genetics mechanisms of resistance and response to tick infestation in Hereford cattle: a global view. Repositório Alice
MORÉ, D. D.; MALAGO JUNIOR, W.; MUDADU, M. A.; ZERLOTINI NETO, A.; GULIAS-GOMES, C. C.; IBELLI, A. M. G.; CATOIA, V.; CARDOSO, F. F.; REGITANO, L. C. A..
The present study aims to analyze the bovine skin transcriptome before and after tick infestation between resistant and susceptible cattle, to identify genes differentially expressed (DE), SNPs in transcribed (QTLs) and regulatory (eQTLs) regions, alternative transcription sites and imprinted genes to draw a map of the skin transcriptome in response to tick infestation.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Gado; Genética; Infestação de carrapatos; Cattle; Genetics; Tick infestations.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/969398
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Genome scan revealed new pathways related to meat tenderness in Nelore beef cattle. Repositório Alice
TIZIOTO, P. L.; DECKER, J. E.; SCHNABEL, R. D.; MUDADU, M. A.; SILVA, F. L.; MOURÃO, G. B.; COUTINHO, L. L.; THOLON, P.; SONSTEGARD, T. S.; ROSA, A. N.; ALENCAR, M. M.; TULLIO, R. R.; MEDEIROS, S. R.; NASSU, R. T.; FEIJÓ, G. L. D.; SILVA, L. O. C.; TORRES, R. A.; SIQUEIRA, F.; HIGA, R. H.; TAYLOR, J. F.; REGITANO, L. C. de A..
A genome wide-association study (GWAS) for Warner-Bratzler shear force (WBSF) measured at different times of meat aging was conducted using genotype data from the Illumina BovineHD BeadChip to identify QTLs in Nelore cattle (n=442).
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Genoma; Gado de corte; Genome; Beef cattle; Nellore.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/969364
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Genome-wide association for growth traits in Canchim beef cattle. Repositório Alice
BUZANSKAS, M. E.; GROSSI, D. A.; VENTURA, R. V.; SCHENKEL, F. S.; SARGOLZAEI, M.; MEIRELLES, S. L. C.; MOKRY, F. B.; HIGA, R. H.; MUDADU, M. A.; SILVA, M. V. G. B.; NICIURA, S. C. M.; TORRES JÚNIOR, R. A. de A.; ALENCAR, M. M.; REGITANO, L. C. A.; MUNARI, D. P..
Abstract. Studies are being conducted on the applicability of genomic data to improve the accuracy of the selection process in livestock, and genome-wide association studies (GWAS) provide valuable information to enhance the understanding on the genetics of complex traits. The aim of this study was to identify genomic regions and genes that play roles in birth weight (BW), weaning weight adjusted for 210 days of age (WW), and long-yearling weight adjusted for 420 days of age (LYW) in Canchim cattle. GWAS were performed by means of the Generalized Quasi-Likelihood Score (GQLS) method using genotypes from the BovineHD BeadChip and estimated breeding values for BW, WW, and LYW. Data consisted of 285 animals from the Canchim breed and 114 from the MA genetic...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Genome-wide association study; Gado de corte; Beef cattle.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1003481
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Global liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes. Repositório Alice
TIZIOTO, P.; COUTINHO, L. L.; DECKER, J. E.; SCHNABEL, R. D.; ROSA, C. O.; OLIVEIRA, P. S. N.; SOUZA, M. M.; MOURÃO, G. B.; TULLIO, R. R.; CHAVES, A. S.; LANNA, D. P. D.; ZERLOTINI NETO, A.; MUDADU, M. A.; TAYLOR, J. F.; REGITANO, L. C. A..
Background: Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock remains poorly understood. Recent developments in molecular genetics, such as platforms for genome-wide genotyping and sequencing, provide an opportunity to identify genes and pathways that influence production traits. It is known that transcriptional networks influence feed efficiency-related traits such as growth and energy balance. This study sought to identify differentially expressed genes in animals genetically divergent for Residual Feed Intake (RFI), using RNA sequencing methodology (RNA-seq) to obtain information from genome-wide...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Transcriptoma; Sequenciamento genético; Bioinformática; Bos indicus; RFI; Feed efficiency; Zebu; Feed conversion; Transcriptomics; Bioinformatics.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1034697
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Initial analysis of copy number variations in canchim beef cattle with extreme phenotypes for ribeye area. Repositório Alice
GIACHETTO, P. F.; PEREIRA, F. C. P.; MOKRY, F. B.; HIGA, R. H.; MUDADU, M. A.; SILVA, M. V.; NICIURA, S. C. M.; CARDOSO, F. F.; ALENCAR, M. M.; MEIRELLES, S. L. C.; LIMA, A. O.; REGITANO, L. C. A..
Genomic structural variation, in the form of large-scale insertions and deletions, as well as inversions and translocations, are referred to as copy number variations (CNVs). Compared to single nucleotide polymorphisms (SNPs), CNVs have potentially greater effects on gene structure, dosage and regulation, being an important source of phenotypic variation. In humans, CNVs are widespread in the genome and have been shown to be associated with complex traits. In livestock species, the characterization of this genetic variation is an important step toward linking genes or genomic regions with phenotypic traits of economic importance. Studies in cattle have revealed some CNVs associated with differences in host parasite resistance and breed-specific differences...
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Variação genética; Polimorfismo de nucleotídeo único; Bioinformática; Copy number variations; Genetic variation; Single nucleotide polymorphisms; Bioinformatics.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/974748
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Imprime registro no formato completo
Initial analysis of copy number variations in canchim beef cattle with extreme phenotypes for ribeye area. Repositório Alice
GIACHETTO, P. F.; PEREIRA, F. C. P.; MOKRY, F. B.; HIGA, R. H.; MUDADU, M. A.; SILVA, M. V.; NICIURA, S. C. M.; CARDOSO, F. F.; ALENCAR, M. M.; MEIRELLES, S. L. C.; LIMA, A. O.; REGITANO, L. C. A..
Genomic structural variation, in the form of large-scale insertions and deletions, as well as inversions and translocations, are referred to as copy number variations (CNVs). Compared to single nucleotide polymorphisms (SNPs), CNVs have potentially greater effects on gene structure, dosage and regulation, being an important source of phenotypic variation. In humans, CNVs are widespread in the genome and have been shown to be associated with complex traits. In livestock species, the characterization of this genetic variation is an important step toward linking genes or genomic regions with phenotypic traits of economic importance. Studies in cattle have revealed some CNVs associated with differences in host parasite resistance and breed-specific differences...
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Variação genética; Polimorfismo de nucleotídeo único; Bioinformática; Copy number variations; Genetic variation; Single nucleotide polymorphisms; Bioinformatics.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/980708
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Monoallelic expression of NNAT gene in Nelore steers skeletal muscle. Repositório Alice
SOUZA, M. M.; ZERLOTINI, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A. L.; MOKRY, F. B.; CESAR, A. S. M.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. A..
ABSTRACT: The NNAT gene plays a role on adipogenesis, brain development and insulin secretion. NNAT is described as paternal imprinted in bovine fetal tissue, but it is still underexplored in adult tissues. In order to improve the understanding of NNAT expression, muscle from Nellore was used to assess its allelic expression. Genomic DNA from 38 steers was genotyped for identification of heterozygous individuals with known allele origin. Total mRNA from muscle was extracted and sequenced by HiScanSQ, and afterwards the reads of each allele were counted for each animal. A total of 8 reciprocal heterozygous had more than 10 reads for the chosen SNP. All animals showed monoallelic expression, being 5 with paternal allele expressed, while 7 had the G allele...
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Neuronatin; Zebu; Genomic imprinting.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1006155
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