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| Registros recuperados: 24 | |
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| Jauffrais, Thierry; Marcaillou-le Baut, Claire; Herrenknecht, Christine; Truquet, Philippe; Sechet, Veronique; Nicolau, Elodie; Tillmann, Urban; Hess, Philipp. |
| Azadinium spinosum (Elbrächter and Tillmann), a small marine dinoflagellate, has been recently described as a de novo producer of azaspiracid-1 and -2 (AZA1 and -2) diarrhoeic toxins. A culture of A. spinosum was established in our laboratory and optimised for pilot-scale production of this organism, to evaluate and understand AZA1 and -2 accumulation and biotransformation in blue mussels (Mytilus edulis) fed with A. spinosum. Adult mussels were continuously exposed to A. spinosum over 1 week in 160 L cylindrical conical tanks. Three different diets were tested for contamination: 5000, 10 000 cells mL−1 of A. spinosum and a mixture of 5000 cells mL−1 of A. spinosum with 5000 cells mL−1 of Isochrysis aff. galbana (T-Iso, CCAP 927/14). During the subsequent... |
| Tipo: Text |
Palavras-chave: Azaspiracid; Azadinium spinosum; Marine biotoxins; AZA; Tissue distribution; Histology; Bivalve molluscs; Liquid chromatography coupled to tandem mass spectrometry. |
| Ano: 2012 |
URL: http://archimer.ifremer.fr/doc/00088/19877/17566.pdf |
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| Haure, Joel; Hussenot, Jerome; Buzin, Florence; Dupuy, Beatrice; Palvadeau, Hubert; Penisson, Christian; Papin, Mathias; Nourry, Max; Lassus, Patrick; Marcaillou-le Baut, Claire; Mondeguer, Florence; Royer, F.; Amzil, Zouher; Belin, Catherine; Cardinal, Mireille; Le Grel, L.; Le Bihan, V.; Jaouen, P.; Massé, A.; Castaing, Jean-baptiste; Sabiri, Ne.; Pontié, M.. |
| La contamination des denrées d’origine marine par des toxines algales (phycotoxines) a pris depuis quelques années une importance considérable. Ce phénomène est largement lié à l’augmentation du nombre de zones géographiques touchées ainsi qu’à la diversification des espèces toxinogènes et à l’identification de nouveaux composés toxiques. Les données épidémiologiques sont cependant encore peu nombreuses car elles sont liées à la mise en place de contrôles systématiques récents. L’Union Européenne a établi un Laboratoire Communautaire de référence pour les phycotoxines, situé à Vigo (Espagne) qui coordonne les activités des laboratoires Nationaux de références correspondants (en France c’est le LNR Phycotoxines de l’AFSSA qui assure cette mission). C’est... |
| Tipo: Text |
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| Ano: 2011 |
URL: http://archimer.ifremer.fr/doc/00092/20277/17922.pdf |
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| Abadie, Eric; Zouher, Amzil; Belin, Catherine; Comps, Marie-annick; Elziere-papayanni, Panayota; Lassus, Patrick; Le Bec, Claude; Marcaillou-le Baut, Claire; Nezan, Elizabeth; Poggi, Robert. |
| A bloom of the toxic dinoflagellate Alexandrium tamarense was observed for the first time in Thau iagoon between November and December 1998. Maximum cell concentrations detected in shellfish farming areas (85 000 Cells/1) were high enough to make mussels and clams unsuitable for human consumption (max. 850 ug. STX eq.100 g'1) while toxic levels in oysters did not exceed, or even reach, the international public health threshold established for PSP toxins. This event, new to French Mediterranean waters, was investigated by both local and national veterinary services and by the Ifremer teams involved in the National Monitoring Network for Phytoplankton and Phycotoxines (Réphy). The chronological and operational description of the event was compared with data... |
| Tipo: Text |
Palavras-chave: Alexandrium; Monitoring; Toxic dinoflagellates; Thau lagoon; Alexandrium; Surveillance; Dinoflagellés toxiques; Etang de Thau. |
| Ano: 1999 |
URL: http://archimer.ifremer.fr/doc/1999/rapport-884.pdf |
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| Marcaillou-le Baut, Claire; Masselin, Pierre; Bohec, Madeleine; Truquet, Philippe; Amzil, Zouher; Pouchus, Francois; Le Boterff, Jean; Verbist, Jean-françois; Vernoux, Jean-paul; Marais, Chantal; Simon, Jean-françois; Nizard, Gabrielle; Mercier, Géraldine; Choumiloff, Roxelan; Baron, Bruno. |
| Cette étude est le résultat d'un travail de trois équipes: elle porte sur la comparaison du test souris avec différents bioessais déjà pratiqués en routine dans les laboratoires participants. Ces bioessais sont : - un test sur micro crustacé dont la méthodologie est normalisée et qui est très utilisé en écotoxicologie aquatique ; - un test de cytotoxicité à court terme qui a été mis au point pour cette étude. |
| Tipo: Text |
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| Ano: 1992 |
URL: http://archimer.ifremer.fr/doc/00139/25035/23144.pdf |
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| Marcaillou-le Baut, Claire. |
| The objective of the study was to pinpoint a possible effect of the food on the decontamination speed up of mussels containing DTX toxins. Studying the possible impact of food on the detoxification rate consists in i) following the toxin content over time for both feeding conditions and ii) checking the physiological state of the animals. For this purpose, an experimental protocol has been designed to describe the kinetics and to compare the detoxification rate in fed and non fed toxic mussels. The experimental disposal was available in an experimental oyster farm where the water and food supply qualities were controlled. The food supply consisted in a monospecific culture of the diatom Skeletonema costatum which is widely used in the shellfish... |
| Tipo: Text |
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| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/00428/53995/55191.pdf |
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| Marcaillou-le Baut, Claire; Haure, Joel; Mondeguer, Florence; Courcoux, Anne; Dupuy, Beatrice; Penisson, Christian. |
| The objective of this study was to identify a possible effect of food on the acceleration of decontamination in blue mussels, Mytilus edulis, containing diarrhetic toxins belonging to the okadaic acid (OA) structural group. An experimental protocol was designed to describe and compare the decontamination kinetics and detoxification rates of naturally OA-contaminated mussels that had either received or not received food for three weeks. The protocol was applied in two trials (in June 2006 and June 2007, called Ker06 and Ker07), conducted one year apart on samples of mussels collected in the same area, at the same season. Okadaic acid (OA), the main lipophilic toxin produced by the toxic alga Dinophysis acuminata, was analysed over the course of the... |
| Tipo: Text |
Palavras-chave: Mussel; Feeding; Digestive gland; Depuration; Okadaic acid; Acyl esters; Marine lipophilic biotoxins; Mass spectrometry. |
| Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/00025/13650/10883.pdf |
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| Marcaillou-le Baut, Claire; Bardin, B.; Bardouil, Michele; Bohec, Madeleine; Le Dean, Loic; Masselin, Pierre; Truquet, Philippe. |
| Two studies of depuration, one in laboratory conditions and the other one in an oyster's pond were performed using 2 sets of contaminated mussels with diarrhetic toxins at a high and a low level (3 and 1 M.U.). Depuration kinetics were followed both by the adult mouse test and okadaïc acid analysis. Results are - in the pond, high toxic mussels need about 20 days to become eatable (toxicity level : 0.5 M.U.g-1 digestive glands), -this time decreases when the initial toxicity is low but it increases when mussels are underfed, - a good correlation is observed between the total toxicity and okadaïc acid concentration. |
| Tipo: Text |
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| Ano: 1990 |
URL: http://archimer.ifremer.fr/doc/00075/18595/16148.pdf |
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| Mondeguer, Florence; Marcaillou-le Baut, Claire. |
| Le littoral français est touché tous les ans par des proliférations d'algues toxiques dont l'ampleur géographique et la durée sont très variables selon les genres/espèces et les années. Par exemple, à partir du mois de mai, voire fin avril certaines années, les côtes sud de la Bretagne et celles des Pays de la Loire sont touchées par des proliférations de Dinophysis spp, genre responsable des intoxications diarrhéiques et cause la plus fréquente des fermetures de zones conchylicoles. Depuis 1988, la côte nord de la Bretagne est exposée à des efflorescences à Alexandrium minutum, producteur de toxines paralysantes. Ces fermetures répétées s'accompagnent d'une diminution, voire d'une cessation d'activité pour les établissements d'expédition car... |
| Tipo: Text |
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| Ano: 2005 |
URL: http://archimer.ifremer.fr/doc/00154/26512/24630.pdf |
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| Fux, E; Marcaillou-le Baut, Claire; Mondeguer, Florence; Bire, R; Hess, Philipp. |
| It has been demonstrated that polymeric resins can be used as receiving phase in passive samplers designed for the detection of lipophilic marine toxins at sea and was referred to as solid phase adsorption toxin tracking (SPATT). The present study describes the uptake and desorption behaviour of the lipophilic marine toxins okadaic acid (OA) and dinophysistoxin-1 (DTX1) from Prorocentrum lima cultures by five styrene-divinylbenzene based polymeric resins Sepabeads (R) SP850, Sepabeads (R) SP825L, Amberlite (R) XAD4, Dowex (R) Optipore (R) L-493 and Diaion (R) HP-20. All resins accumulated OA and DTX1 from the P. lima culture with differences in adsorption rate and equilibrium rate. Following statistical evaluation, HP-20, SP850 and SP825L demonstrated... |
| Tipo: Text |
Palavras-chave: Polymeric resin; Dinophysistoxin 1; Okadaic acid; SPATT; Prorocentrum lima. |
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/2008/publication-4739.pdf |
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| Lassus, Patrick; Gowland, Denis; Mckenzie, Douglas; Kelly, Kelly; Braaten, Bjoern; Marcaillou-le Baut, Claire; Blanco, Juan. |
| As early as 1999, the EUROHAB initiative reported an urgent need for research on phycotoxin accumulation, detoxification and biotransformation rates in exploited shellfish species. It also strongly recommended a second objective of developing commercial systems for the cleansing of shellfish once contaminated with toxin. As a result, EU Framework Programs and regional programs funded a series of R & D projects aiming to consolidate our understanding of contamination/detoxification pathways, together with the development of industrial scale detoxification processes and mechanisms. These studies attempted to accelerate the depuration process, for DSP in blue mussels, PSP in Pacific oysters and Manila clams, and ASP in King Scallops. Bulk culture... |
| Tipo: Text |
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| Ano: 2009 |
URL: http://archimer.ifremer.fr/doc/00015/12575/9445.pdf |
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| Registros recuperados: 24 | |
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