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Lung clearance of 99mTc-DTPA in systemic lupus erythematosus BJMBR
Dalcin,P.T.R.; Barreto,S.S.M.; Cunha,R.D.; Xavier,R.M.; Brenol,J.C.T.; Marroni,B.J..
The early demonstration of lung involvement in systemic lupus erythematosus (SLE) patients is a difficult but important task. In the present study we attempted to identify abnormalities in pulmonary clearance of 99mTc-DTPA in SLE, correlating their clearance data with clinical findings and disease activity. Forty-six consecutive SLE patients with and without active disease (LACC score) and 30 normal volunteers were studied. All subjects were submitted to pulmonary scintigraphy with 99mTc-DTPA to evaluate the pulmonary clearance, and to a chest X-ray, and SLE patients were submitted to tests of disease activity, spirometry, arterial blood gases and tests to assess acute-phase proteins. Pulmonary clearance was faster in SLE patients with active disease when...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pulmonary epithelial permeability; Lung clearance; Technetium-99m-labeled diethylenetriamine pentaacetic acid; Systemic lupus erythematosus.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000600005
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