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| Franco,M.C.P.; Nagasako,S.S.; Machado,P.G.; Nogueira,P.C.K.; Pestana,J.O.M.; Sesso,R.. |
| In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation between GFR estimated by serum creatinine and by cystatin C was significant (r = 0.75; P < 0.001, Person’s correlation); however, in pediatric kidney transplant recipients, the GFR was 6.7 mL/min lower when determined using cystatin C rather than serum creatinine. Moreover, using GFR estimated by cystatin C we found that 42% of the pediatric kidney transplant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Children; Kidney transplant; Cystatin C; Creatinine; Glomerular filtration rate. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200017 |
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