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Antinociceptive effects of the essential oil of Croton zehntneri in mice BJMBR
Oliveira,A.C.; Leal-Cardoso,J.H.; Santos,C.F.; Morais,S.M.; Coelho-de-Souza,A.N..
Croton zehntneri is an aromatic plant native to Northeastern Brazil, where it is often used in folk medicine. In the present study the antinociceptive effects of the essential oil of Croton zehntneri (EOCz) were evaluated in mice. EOCz administered orally at doses of 100 and 300 mg/kg reduced paw licking time in the second phase of the formalin test from the control value of 41.61 ± 8.62 to 12.01 ± 7.97 and 6.57 ± 3.42 s, respectively. During the first phase of the formalin test only 300 mg/kg induced a significant alteration (from 58.2 ± 7.02, control, to 28.7 ± 4.73 s). The number of contortions in response to intraperitoneal injections of acetic acid did not differ significantly between controls (80.6 ± 9.01) and experimental (300 mg/kg body weight)...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Croton zehntneri; Essential oil; Analgesic; Antinociception; Formalin test; Hot-plate test.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001100016
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Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice BJMBR
Sousa,P.J.C.; Linard,C.F.B.M.; Azevedo-Batista,D.; Oliveira,A.C.; Coelho-de-Souza,A.N.; Leal-Cardoso,J.H..
Mentha x villosa Huds (Labiatae) is an aromatic herb widely used in folk medicine. Since the essential oil of the herb has many pharmacological activities, including antispasmodic effects, we determined whether the oil and its major constituent, piperitenone oxide (PO), have antinociceptive activity. The essential oil of M. x villosa (EOMV) and PO administered orally at 200 mg/kg (vehicle: 0.1% Tween 80 in water) significantly reduced the writhings induced by acetic acid from control values of 59.5 ± 3.1 s (N = 10) to 31.9 ± 2.8 s (N = 10) and 23.8 ± 3.4 s (N = 10), respectively. When administered at 100 and 200 mg/kg, EOMV reduced the paw licking time for the second phase of the formalin test from the control value of 20.6 ± 2.1 s (N = 13) to 5.3 ± 2.2 s...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Mentha x villosa essential oil; Analgesia; Nociception; Anti-inflammatory effect; Piperitenone oxide.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000700010
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Babesia spp. no líquido peritoneal em cão com ascite - relato de caso Arq. Bras. Med. Vet. Zootec.
Cota,J.M.; Orozco,A.M.O.; Bedoya,S.A.O.; Oliveira,A.C.; Viloria,M.I.V.; Costa,P.R.S..
RESUMO Babesia canis é um protozoário cosmopolita que parasita eritrócitos de cães domésticos e selvagens. O diagnóstico é realizado mediante a observação direta do microrganismo em hemácias no esfregaço de sangue periférico, métodos sorológicos e técnicas moleculares. O objetivo deste trabalho é relatar pela primeira vez a presença de merozoítos de Babesia spp. no líquido peritoneal de um cão com ascite. No Hospital Veterinário da Universidade Federal de Viçosa, foi atendido um cão, macho, sem raça definida, de sete meses de idade, com histórico de emaciação, apatia e abaulamento abdominal. No exame físico, foram evidenciadas mucosas hipocoradas, ascite, sopro sistólico grau IV/V e taquipneia. Nos exames laboratoriais, evidenciou-se anemia...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cães; Protozoário; Líquido peritoneal; Ascite.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000401109
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Chemical composition and fermentation characteristics of sugar cane silage enriched with detoxified castor bean meal Arq. Bras. Med. Vet. Zootec.
Oliveira,A.C.; Garcia,R.; Pires,A.J.V.; Oliveira,H.C.; Almeida,V.V.S.; Silva,R.R.; Nascimento Filho,C. Souza; Abreu Filho,G..
This experiment was designed to evaluate the effects of the inclusion of detoxified castor bean meal (CM) content on the chemical-bromatological composition, as well as the fermentation characteristics and dry matter losses of sugarcane silage. The treatments consisted of four levels (0, 7, 14 and 21% natural matter) of addition of castor bean meal. The design was completely randomized, with five replicates. The material was ensiled in PVC silos of 50-cm in height and 10-cm in diameter, which were opened after 60 days. The density of fodder maintained in the silos was equal to 750kg of natural matter/m3. In order to quantify the gas and effluent losses, the silos were weighed at the beginning and at the end of the experiment. The addition of castor bean...
Tipo: Info:eu-repo/semantics/article Palavras-chave: By-product; Ethanol; Gases; Saccharum officinarum L; Silage.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000100181
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Differential gene expression profiles of hepatocellular carcinomas associated or not with viral infection BJMBR
Bellodi-Privato,M.; Kubrusly,M.S.; Stefano,J.T.; Soares,I.C.; Wakamatsu,A.; Oliveira,A.C.; Alves,V.A.F.; Bacchella,T.; Machado,M.C.C.; D’Albuquerque,L.A.C..
Chronic hepatitis B (HBV) and C (HCV) virus infections are the most important factors associated with hepatocellular carcinoma (HCC), but tumor prognosis remains poor due to the lack of diagnostic biomarkers. In order to identify novel diagnostic markers and therapeutic targets, the gene expression profile associated with viral and non-viral HCC was assessed in 9 tumor samples by oligo-microarrays. The differentially expressed genes were examined using a z-score and KEGG pathway for the search of ontological biological processes. We selected a non-redundant set of 15 genes with the lowest P value for clustering samples into three groups using the non-supervised algorithm k-means. Fisher’s linear discriminant analysis was then applied in an exhaustive...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatocellular carcinoma; Molecular biomarkers; Viral infection; Oligo-microarrays.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200001
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Does hepatocellular carcinoma in non-alcoholic steatohepatitis exist in cirrhotic and non-cirrhotic patients? BJMBR
Chagas,A.L.; Kikuchi,L.O.O.; Oliveira,C.P.M.S.; Vezozzo,D.C.P.; Mello,E.S.; Oliveira,A.C.; Cella,L.C.; Herman,P.; Bachella,T.; Caldwell,S.H.; Alves,V.A.F.; Carrilho,F.J..
Non-alcoholic steatohepatitis (NASH) has been associated with hepatocellular carcinoma (HCC) often arising in histologically advanced disease when steatohepatitis is not active (cryptogenic cirrhosis). Our objective was to characterize patients with HCC and active, histologically defined steatohepatitis. Among 394 patients with HCC detected by ultrasound imaging over 8 years and staged by the Barcelona Clinic Liver Cancer (BCLC) criteria, we identified 7 cases (1.7%) with HCC occurring in the setting of active biopsy-proven NASH. All were negative for other liver diseases such as hepatitis C, hepatitis B, autoimmune hepatitis, Wilson disease, and hemochromatosis. The patients (4 males and 3 females, age 63 ± 13 years) were either overweight (4) or obese...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Hepatocellular carcinoma; Liver cancer; Fatty liver; Steatohepatitis; Cirrhosis.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000014
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Effects of weed "Reestablishment" after hoeing on corn yields Planta Daninha
Silva,P.S.L.; Oliveira,A.C.; Oliveira,O.F.; Freitas,F.C.L.; Santos,T.S..
Some growers and researchers sustain the idea that regrowth or root setting of some weeds may occur after hoeing, with detrimental effects over corn. The objective of this study was to evaluate the effects of weed removal from the field, removal after each hoeing, and corn intercropped with gliricidia on weed control and corn yield values. The experimental design consisted of blocks with split-plots and six replicates. Cultivars AG 1051 and BM 2022, planted in the plots, were submitted to the following treatments: no hoeing, two hoeings (at 20 and 40 days after planting), and intercropped with gliricidia. The hoed plots were either submitted to weed removal after the first, second, or both hoeings, or remained without weed removal. In the intercropped...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zea mays; Gliricidia sepium; Green ear yield; Grain yield.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582010000200007
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Essential oil of Pterodon polygalaeflorus Benth attenuates nociception in mice BJMBR
Coelho-de-Souza,A.N.; dos-Santos,C.F.; Lopes-Filho,L.N.; Holanda,F.R.; Oliveira,A.C.; Gomes-Vasconcelos,Y.A.; Oliveira,K.A.; Ferreira-da-Silva,F.W.; Silva-Alves,K.S.; Leal-Cardoso,J.H..
Essential oils (EO) are volatile liquids responsible for the aroma of plants. Pterodon polygalaeflorus seeds have received widespread use in folk medicine for the treatment of inflammatory diseases. For this reason and because Pterodon polygalaeflorus seeds have great EO content, which is frequently pharmacologically active, the present study aimed to evaluate the antinociceptive effect of EO from Pterodon polygalaeflorus (EOPPgfl) and its acute toxic effects. The EEOPPgfl sample, which was extracted by steam distillation of the seeds, had a yield of 2.4% of the seeds weight and had, as major constituents, beta-elemene (48.19%), trans-caryophyllene (19.51%), and epi-bicyclosesquiphellandrene (12.24%). The EOPPgfl sample showed mild acute toxicity and its...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Essential oil; Pterodon polygalaeflorus; Antinociception; Anti-inflammatory activities; Beta-elemene; Caryophyllene.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001100603
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Hereditary angioedema with C1 inhibitor (C1-INH) deficit: the strength of recognition (51 cases) BJMBR
Fragnan,N.T.M.L.; Tolentino,A.L.N.; Borba,G.B.; Oliveira,A.C.; Simões,J.A.; Palma,S.M.U.; Constantino-Silva,R.N.; Grumach,A.S..
Hereditary angioedema (HAE) is a rare autosomal dominant disease due to C1 esterase inhibitor deficiency (C1-INH). The disease is characterized by subcutaneous and submucosal edema in the absence of urticaria due to the accumulation of bradykinin. This descriptive study aimed to evaluate the clinical characteristics of patients with a confirmed diagnosis of HAE referred to our Outpatient Clinic between December 2009 and November 2017. Fifty-one patients (38 F, 13 M) with a mean age of 32 years (range: 7–70 y) were included. Family history of HAE was reported in 70% (36/51) of the cases; 33/46 patients became symptomatic by 18 years of age. The median time between onset of symptoms and diagnosis was 13 years (3 mo–50 y). The most frequent triggering factors...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hereditary angioedema; C1 esterase inhibitor; Diagnosis; Treatment; Complement.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200607
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Low prevalence of relevant findings in inappropriate echocardiograms and discordant perceptions between cardiologists and patients BJMBR
Lopes,J.R.; Oliveira,A.C.; Rios,V.G.; Correia,L.C.L..
Complementary examinations are “inadequate” whenever the likelihood of benefits from their indication is lower than the negative results. The low benefit is a result of poor performance in detecting relevant changes that lead to improved behavior. However, inadequate examinations are prevalent and little is known about patients' notions of the usefulness of such indications. The aim of this study was to describe relevant findings in inappropriate echocardiograms and to assess the level of agreement between patients and cardiologists regarding their usefulness. Adults without known cardiovascular disease who were referred for echocardiogram by inappropriate criteria according to the American College of Cardiology were selected. Relevant findings were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Echocardiogram; Inappropriate; Utility; Patients; Cardiologists.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800606
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New concepts in white adipose tissue physiology BJMBR
Proença,A.R.G.; Sertié,R.A.L.; Oliveira,A.C.; Campaãa,A.B.; Caminhotto,R.O.; Chimin,P.; Lima,F.B..
Numerous studies address the physiology of adipose tissue (AT). The interest surrounding the physiology of AT is primarily the result of the epidemic outburst of obesity in various contemporary societies. Briefly, the two primary metabolic activities of white AT include lipogenesis and lipolysis. Throughout the last two decades, a new model of AT physiology has emerged. Although AT was considered to be primarily an abundant energy source, it is currently considered to be a prolific producer of biologically active substances, and, consequently, is now recognized as an endocrine organ. In addition to leptin, other biologically active substances secreted by AT, generally classified as cytokines, include adiponectin, interleukin-6, tumor necrosis factor-alpha,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adipose tissue; Lipogenesis; Lipolysis; Adipogenesis; Endocrine.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000300192
Registros recuperados: 11
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