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Registros recuperados: 101 | |
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VERARDO, L. L.; STAFUZZA, N. B.; MUNARI, D. P.; ZERLOTINI NETO, A.; CHUD, T. C. S.; GARRICK, D. J.; COLE, J. B.; PANETTO, J. C. do C.; MACHADO, M. A.; MARTINS, M. F.; SILVA, M. V. G. B.. |
The aim of this study was to analyze whole-genome re-sequencing data focusing on SNVs and InDels identified in Gir, Girolando and Holstein cattle breeds related to RFI. Thus, genes showing SNVs/InDels in TF binding sites (5' UTR variants) were used to search for TF related to feed intake and to generate a gene-TF network for RFI across two purebred and one admixed dairy cattle breeds. Moreover, we were able to perform a comparative analysis accessing similarities and dissimilarities at the genomic level across these breeds. |
Tipo: Anais e Proceedings de eventos |
Palavras-chave: Sequência de dados; Single Nucleotide Variations (SNVs); Insertions/deletions (InDels); Whole-genome; Whole-genome re-sequencing data; Gado de Corte; Bos Indicus; Variação Genética; Cattle breeds. |
Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1105518 |
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PERIPOLLI, E.; STAFUZZA, N. B.; MACHADO, M. A.; PANETTO, J. C. do C.; EGITO, A. A. do; BALDI, F.; SILVA, M. V. G. B.. |
Further characterization of genetic structural variations should strongly focus on small and endangered local breeds given their role in unraveling genes and structural variants underlying selective pressures and phenotype variation. A comprehensive genome-wide assessment of copy number variations (CNVs) based on whole-genome re-sequencing data was performed on three Brazilian locally adapted cattle breeds (Caracu Caldeano, Crioulo Lageano, and Pantaneiro) using the ARS-UCD1.2 genome assembly. Data from 36 individuals with an average coverage depth of 14.07× per individual was used. A total of 24?945 CNVs were identified distributed among the breeds (Caracu Caldeano = 7285, Crioulo Lageano = 7297, and Pantaneiro = 10 363). Deletion events were... |
Tipo: Artigo de periódico |
Palavras-chave: Variação fenotípica; Bovino; Raça; Gado Crioulo; Genoma. |
Ano: 2023 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1151656 |
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PERIPOLLI, E.; STAFUZZA, N. B.; MUNARI, D. P.; LIMA, A. L. F.; IRGANG, R.; MACHADO, M. A.; PANETTO, J. C. do C.; VENTURA, R. V.; BALDI, F.; SILVA, M. V. G. B.. |
Abstract BACKGROUND: Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i) to investigate genome-wide autozygosity to identify and characterize ROH patterns in Gyr dairy cattle genome; (ii) identify ROH islands for gene content and enrichment in segments shared by more than 50% of the samples, and (iii) compare estimates of molecular inbreeding calculated from ROH (FROH), genomic relationship matrix approach (FGRM) and based on the observed versus expected number of homozygous genotypes (FHOM), and from pedigree-based coefficient (FPED). RESULTS: ROH were identified in... |
Tipo: Separatas |
Palavras-chave: Dairy traits; Inbreeding coefficients; ROH islands; Bos Indicus. |
Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1100275 |
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PERIPOLLI, E.; OLIVIERI. B. F.; FEITOSA, F. L. B.; LEMOS, M. V. A. de; TONUSSI, R. L.; MUNARI, D. P.; PANETTO, J. C. do C.; MACHADO, M. A.; VENTURA, R. V.; BALDI, F.; SILVA, M. V. G. B.. |
Tipo: Separatas |
Palavras-chave: Autozigosidade; Corridas de Homozigose.; Pedigree.. |
Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1072487 |
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MALUF, V. H. H. K.; LIMA, T. R. de; CAMPOS, R. A.; SOARES, I. K. de A.; PEREIRA, H. P.; DOMINGUES, R.; REIS, D. R. de L.; MARTINS, M. F.; PANETTO, J. C. do C.; SILVA, M. V. G. B.; MACHADO, M. A.. |
O leite é um alimento rico em nutriente e proteínas, sendo um alimento muito importante na saúde humana. A beta caseína é uma das proteínas mais abundantes no leite bovino, e 12 variantes já foram descritas na literatura. As mais encontradas são as variantes A1 e A2, que diferem entre si por uma troca de nucleotídeo (SNP), que acarreta uma troca de aminoácido. A digestão da beta caseína A1 no trato gastrintestinal humano tem como um de seus produtos finais um peptídeo bioativo denominado beta casomorfina 7, que foi relacionado a várias doenças em humanos. Amostras de DNA de touros da raça Girolando, previamente genotipados para este SNP, foram usados para o desenvolvimento de uma metodologia de genotipagem por tetra-primer ARMS-PCR. Após várias... |
Tipo: Anais e Proceedings de eventos |
Palavras-chave: Beta-caseína; A1A2; Genotipagem; ARMS-PCR; Bovino. |
Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1134696 |
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REIS, D. R. de L.; PEREIRA, H. P.; EGITO, A. A. do; TORRES JUNIOR, R. A. de A.; KIM, E. S.; SONSTEGARD, T. S.; MARTINS, M. F.; PANETTO, J. C. do C.; SILVA, M. V. G. B.; MACHADO, M. A.. |
Communication. |
Tipo: Artigo de periódico |
Palavras-chave: Gado. |
Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1134440 |
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DALTRO, D. dos S.; SILVA, M. V. G. B.; GAMA, L. T. da; MACHADO, J. D.; KERN, E. L.; CAMPOS, G. S.; PANETTO, J. C. do C.; COBUCI, J. A.. |
The objective of this work was to evaluate the effects of breed and heterosis on the estimates of genetic parameters of 305-day milk yield (305MY), by fitting milk yield data to the Wood, Mixed Log, Morgan, and Wilmink non-linear models. A total of 258,891 test-day milk yield records of 37,965 Holstein (H), Gyr (G), and Girolando (1/2 H, 1/4 H, 3/4 H, 3/8 H, 5/8H and 7/8H genetic groups) cows from 1840 herds were collected in the state of Minas Gerais, Brazil, in the period of 1998 to 2014. The pedigree file included 36,640 animals, 3677 bulls and 24,472 cows. The genetic parameters were obtained by one-character analysis using the AIREMLF90 software. The heritability estimates of 305MY, and of 305MY fitted to the different nonlinear models ranged from... |
Tipo: Artigo de periódico |
Palavras-chave: Heterose; Vaca Leiteira; Gado Leiteiro; Modelo Matemático; Bovino; Dairy cows; Heritability; Heterosis; Mathematical models. |
Ano: 2020 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1133496 |
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NASCIMENTO, J. C.; SEIBERLICK, O. S. G.; CARVALHO, B. O.; PEREIRA, H. P.; REIS, D. R. de L.; MARTINS, M. F.; PANETTO, J. C. do C.; MACHADO, M. A.; SILVA, M. V. G. B.. |
Resumo: Em ambientes tropicais e subtropicais, a expressão de características produtivas em bovinos é dificultada pelos efeitos ambientais como o estresse térmico, agravado pelo aquecimento global. Regiões genômicas associadas à tolerância ao calor foram recentemente descritas e polimorfismos de nucleotídeos únicos (SNPs) relacionados a essa variação foram identificados. Uma mutação no gene do receptor de prolactina, no SNP 39136666 foi relacionada à presença de um tipo diferente de pelagem denominada “slick hair” em animais da raça Carora e Caracu, que está associado com a maior tolerância ao calor. Foram genotipados neste trabalho, 61 animais da raça Cararu Caldeano, utilizando a técnica tetra-primers ARMSPCR. A frequência alélica e genotípica foi... |
Tipo: Anais e Proceedings de eventos |
Palavras-chave: Genotipagem; Caracu caldeano; Tetra-primer; ARNS-PCR. |
Ano: 2019 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1112049 |
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RIBEIRO, V. M. P.; MERLO, F. A.; GOUVEIA, G. C.; WINKELSTROTER, L. K.; ABREU, L. R. A.; SILVA, M. V. G. B.; PANETTO, J. C. do C.; PAIVA, L. de C.; CEMBRANELLI, M. de A. R.; TORAL, F. L. B.. |
The objective of this work was to determine whether the random regression model using linear splines (RRMLS) is suitable to estimate the genetic parameters for productive and reproductive traits of a multiple-breed dairy cattle population, as well as to investigate the effect of the genetic group of the progeny on the genetic merit of the sire. The multiple-trait model (MTM) and the RRMLS with one knot fitted for every genetic group were used to obtain the genetic parameters. Records of 1/2 Holstein + 1/2 Gyr (1/2HG), 5/8 Holstein + 3/8 Gyr (5/8HG), and 3/4 Holstein + 1/4 Gyr (3/4HG) crossbreed dams were considered. The RRMLS showed better fitting. The additive and residual variances estimated by the MTM and the RRMLS were similar. Heritability varied from... |
Tipo: Separatas |
Palavras-chave: Raça Gir.; Gir (cattle breed).. |
Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1083465 |
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ZANELLA, R.; LAGO, L. V.; SILVA, A. N. da; PÉRTILLE, F.; CARVALHO, N. S. de; PANETTO, J. C. do C.; ZANELLA, G. C.; FACIOLI, F. L.; SILVA, M. V. G. B.. |
Abstract The Indubrasil breed was developed in the Brazilian region called Triângulo Mineiro as a result of a cross between zebu cattle. Initially, it was used as a terminal cross and currently it represents approximately 4.45% of all the Brazilian zebu cattle. Studies were conducted to estimate genetic parameters in the Indubrasil using pedigree information, however, until now, no study has been developed using large-scale genomic markers in this breed. Pedigree information are widely used to investigate population parameters; however, they can neglect some estimates when compared to the use of genomic markers. Therefore, the objective of this study was to investigate the population structure and the genetic diversity of Indubrasil cattle using a... |
Tipo: Separatas |
Palavras-chave: Indubrasil; SNPs; Genetic diversity; Inbreeding; Pedigree. |
Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1101944 |
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CARVALHO, N. S.; DALTRO, D. S.; MACHADO, J. D.; CAMARGO, E. V.; PANETTO, J. C. do C.; COBUCI, J. A.. |
The objective of this study was to estimate genetic parameters and genetic trends of different conformation and management traits regularly measured within the context of the National Dairy Gir Breeding Program (PNMGL). The estimation of genetic and residual variances for each trait was performed using average information restricted maximum likelihood (AI-REML) procedure in AIREMLF90 program software. The population was divided into three subpopulations constituted by measured females (with phenotype records), all females, and males. Linear regressions were applied for each trait, considering two periods of birth (1st period: 1938-1996; 2nd period: 1997-2012). The estimated heritability of conformation and management traits varied from 0.01 to 0.53,... |
Tipo: Artigo de periódico |
Palavras-chave: Progresso genético; Genetic progress; Bovino; Melhoramento Genético Animal; Gado Zebu; Bos Taurus; Teste de Progênie; Progeny testing. |
Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1134796 |
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REGITANO, L. C. de A.; VERARDO, L. L.; SILVA, F. F. e; MACHADO, M. A.; PANETTO, J. C. do C.; REIS, D. R. de L.; OTTO, P. I.; SILVA, M. V. G. B.; ZANELLA, R.; ALBUQUERQUE, M. do S. M.; EGITO, A. A. do; SILVA, L. O. C. da. |
Cattle population history, breeding systems, and geographic subdivision may be reflected in runs of homozygosity (ROH), effective population size (Ne), and linkage disequilibrium (LD) patterns. Thus, the assessment of this information has become essential to the implementation of genomic selection on purebred and crossbred cattle breeding programs. In this way, we assessed the genotype of 19 cattle breeds raised in Brazil belonging to taurine, indicine, synthetic crossbreds, and Iberian-derived locally adapted ancestries to evaluate the overall LD decay patterns, Ne, ROH, and breed composition. We were able to obtain a general overview of the genomic architecture of cattle breeds currently raised in Brazil and other tropical countries. We found that, among... |
Tipo: Artigo de periódico |
Palavras-chave: Rusticidade; Rusticity; Bovino; Gado; Genética Animal; Genoma; Produção Leiteira; Comportamento Animal; Fertilidade Animal; Homozygosity; Population size; Linkage disequilibrium; Milk production; Animal behavior; Animal fertility. |
Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1133730 |
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Registros recuperados: 101 | |
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