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Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development Inra
Pantalacci, S.; Prochazka, J.; Martin, A.; Rothova, M.; Lambert, A.; Bernard, L.; Charles, C.; Viriot, L.; Peterkova, R.; Laudet, V..
Background: The development of the secondary palate has been a main topic in craniofacial research, as its failure results in cleft palate, one of the most common birth defects in human. Nevertheless, palatal rugae (or rugae palatinae), which are transversal ridges developing on the secondary palate, received little attention. However, rugae could be useful as landmarks to monitor anterior/posterior (A/P) palatal growth, and they provide a simple model of mesenchymal-epithelial structures arranged in a serial pattern.Results: We first determined in which order the nine mouse rugae appear during development. Our results revealed a reiterative process, which is coupled with A/P growth of palatal shelves, and by which rugae 3 to 7b are sequentially...
Tipo: Journal Article Palavras-chave: FENTE PALATINE; POLARITÉ DÉVELOPPEMENT; DÉVELOPPEMENT EMBRYONNAIRE.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200945f42261&uri=/notices/prodinra1/2009/12/
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