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Contribution of flagella and motility to gut colonisation and pathogenicity of Salmonella Enteritidis in the chicken BJM
Barbosa,Fernanda de Oliveira; Freitas Neto,Oliveiro Caetano de; Batista,Diego Felipe Alves; Almeida,Adriana Maria de; Rubio,Marcela da Silva; Alves,Lucas Bocchini Rodrigues; Vasconcelos,Rosemeire de Oliveira; Barrow,Paul Andrew; Berchieri Junior,Angelo.
ABSTRACT Salmonella Enteritidis causes fowl paratyphoid in poultry and is frequently associated to outbreaks of food-borne diseases in humans. The role of flagella and flagella-mediated motility into host-pathogen interplay is not fully understood and requires further investigation. In this study, one-day-old chickens were challenged orally with a wild-type strain Salmonella Enteritidis, a non-motile but fully flagellated (SE ΔmotB) or non-flagellated (SE ΔfliC) strain to evaluate their ability to colonise the intestine and spread systemically and also of eliciting gross and histopathological changes. SE ΔmotB and SE ΔfliC were recovered in significantly lower numbers from caecal contents in comparison with Salmonella Enteritidis at early stages of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mutation; Flagellum; Virulence factors; Poultry; Gut colonisation.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000400754
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Effects of mycotoxin adsorbents in aflatoxin B 1 - and fumonisin B 1 -contaminated broiler diet on performance and blood metabolite R. Bras. Zootec.
Sobrane Filho,Sérgio Turra; Junqueira,Otto Mack; Laurentiz,Antonio Carlos de; Filardi,Rosemeire da Silva; Rubio,Marcela da Silva; Duarte,Karina Ferreira; Laurentiz,Rosangela da Silva de.
ABSTRACT The present study examined the effect of aflatoxin (AFB1) and fumonisin (FB1) at the levels of 2 mg kg−1 AFB1 and 100 mg kg−1 FB1 and the efficiency of use of different levels of adsorbent based on sodium and calcium aluminosilicate on growth performance, hematological parameters, and biochemical parameters of broilers. A total of 1,440 Cobb broilers were distributed into the following treatments: positive control (PC) - no mycotoxin and adsorbent (AD); PC+3AD - no mycotoxin, with 3 g kg−1 adsorbent in feed; negative control (NC) - only mycotoxin; NC+1AD - with mycotoxin and 1 g kg−1 adsorbent in feed; NC+2AD - with mycotoxin and 2 g kg−1 adsorbent in feed; and NC+3AD - with mycotoxin and 3 g kg−1 adsorbent in feed. The amounts of AFB1 and FB1...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biochemical parameter; Feeding; Growth performance; Hematological parameter mycotoxicosis; Mycotoxins.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016000500250
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Inactivation of phoPQ genes attenuates Salmonella Gallinarum biovar Gallinarum to susceptible chickens BJM
Alves,Lucas Bocchini Rodrigues; Freitas Neto,Oliveiro Caetano de; Batista,Diego Felipe Alves; Barbosa,Fernanda de Oliveira; Rubio,Marcela da Silva; Souza,Andrei Itajahy Secundo de; Almeida,Adriana Maria de; Barrow,Paul Andrew; Berchieri Junior,Angelo.
Abstract Salmonella Gallinarum is a host-restrict pathogen that causes fowl typhoid, a severe systemic disease that is one of the major concerns to the poultry industry worldwide. When infecting the bird, SG makes use of evasion mechanisms to survive and to replicate within macrophages. In this context, phoPQ genes encode a two-component regulatory system (PhoPQ) that regulates virulence genes responsible for adaptation of Salmonella spp. to antimicrobial factors such as low pH, antimicrobial peptides and deprivation of bivalent cations. The role of the mentioned genes to SG remains to be investigated. In the present study a phoPQ-depleted SG strain (SG ΔphoPQ) was constructed and its virulence assessed in twenty-day-old laying hens susceptible to fowl...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mutation; Virulence; Fowl typhoid; Adaptation; Chickens.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300601
Registros recuperados: 3
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