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| Registros recuperados: 106 | |
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| HAACH, V.; BASTOS, A. P. A.; GAVA, D.; FONSECA, F. M. da.; MORES, M. A. Z.; COLDEBELLA, A.; FRANCO, A. C.; SCHAEFER, R.. |
| Abstract: Background: Influenza A virus (IAV) is endemic in pigs globally and co-circulation of genetically and antigenically diverse virus lineages of subtypes H1N1, H1N2 and H3N2 is a challenge for the development of effective vaccines. Virosomes are virus-like particles that mimic virus infection and have proven to be a successful vaccine platform against several animal and human viruses. Methods: This study evaluated the immunogenicity of a virosome-based influenza vaccine containing the surface glycoproteins of H1N1 pandemic, H1N2 and H3N2 in pigs. Results: A robust humoral and cellular immune response was induced against the three IAV subtypes in pigs after two vaccine doses. The influenza virosome vaccine elicited hemagglutinin-specific antibodies... |
| Tipo: Artigo de periódico |
Palavras-chave: Virosomal vaccine; Cellular immunity; Suíno; Vacina; Imunidade; Swine; Humoral immunity; Influenza A virus. |
| Ano: 2023 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1156557 |
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| SILVA, M. C. da; SCHAEFER, R.; GAVA, D.; SOUZA, C. K.; VENANCIO, E. J.. |
| Introduction and objectives: Influenza is a disease caused by infection of the host respiratory tract by influenza type A virus that affects a wide variety of species, including human, swine, equine, poultry and sea mammals. The viral RNA is encapsidated by the nucleoprotein (NP), which is a highly conserved protein among influenza A viruses. Detection of influenza virus can be accomplished by assessing specific immune response to the virus, by direct detection of viral RNA or virus antigen in infected tissues. Some diagnostic tests use antibodies produced in mammals to influenza virus detection. However, due to high cost and concerns related to animal welfare, alternative production of antibodies in mammals has been described. The immunoglobulin Y (IgY)... |
| Tipo: Separatas |
Palavras-chave: Imunocitoquímica; IgY.; Sanidade animal; Virologia; Imunologia.; Immunoglobulin Y; Influenza.. |
| Ano: 2017 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1078687 |
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| HAACH, V.; BASTOS, A. P. A.; GAVA, D.; FONSECA, F. M. da; MORES, M. A. Z.; COLDEBELLA, A.; FRANCO, A. C.; SCHAEFER, R.. |
| Influenza A virus (IAV) causes economic losses to the swine industry and public health concerns. The IAV is endemic in pigs and genetically and antigenically distinct virus lineages of subtypes H1N1, H1N2 and H3N2 circulate in different geographic regions with limited cross-protection (1, 2). The co-circulation of distinct IAV lineages associated with rapid viral evolution challenges the development of effective vaccines. The aim of this study was to evaluate the immunogenicity of an adjuvanted virosome-based influenza vaccine containing the hemagglutinin (HA) of H1N1pdm, H1N2 and H3N2. |
| Tipo: Parte de livro |
Palavras-chave: Imunidade celular; Suinocultura; Vacinação; Vacina Polivalente; Influenza A virus. |
| Ano: 2022 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1146658 |
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| DAMBRÓS, R. M. F.; RIBEIRO, B. M.; AGUIAR, R. W. de S.; SCHAEFER, R.; ESTEVES, P. A.; PERECMANIS, S.; SIMON, N. L.; SILVA, N. C.; COLDEBELLA, M.; ZANELLA, J. R. C.. |
| Projeto n. 03.03.23.200 |
| Tipo: Separatas |
Palavras-chave: Glicoproteina E.; Baculovirus; Doença de Aujeszky; Suíno.. |
| Ano: 2007 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/443629 |
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| Registros recuperados: 106 | |
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