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Different culture media applied to the study of Cryptococcus neoformans susceptibility to amphotericin B and fluconazole BJM
Alves,Sydney Hartz; Oliveira,Loiva T.; Goulart,Letícia S.; Linares,Carlos Eduardo B.; Griebeler,Josiane; Santurio,Janio M..
This study compared the performance of three culture media used for the determination of minimal inhibitory concentration (MIC) of amphotericin B and fluconazole against 48 Cryptococcus neoformans strains. For amphotericin B the media employed were RPMI 1640 medium, as indicated by NCCLS as reference, Yeast Nitrogen Base (YNB) as proposed by Ghannoum et al. (YNB-1), Antibiotic medium 3 (AM3) indicated by others, and YNB as proposed by us (YNB-2). In YNB-1, amphotericin B showed broader MIC ranges, varying from 0.125 µg/ml to 1.0 µg/ml; in RPMI 1640 medium and YNB-2 the MICs were similar and in AM3 the MIC ranges were narrower. The same pattern was observed for MIC 90%. For fluconazole the media employed were RPMI 1640 and YNB-1. The MIC ranges were broader...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptococcus neoformans; Susceptibility; Antifungal agents.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822002000100005
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Equine leukoencephalomalacia associated with ingestion of corn contaminated with fumonisin B1 Rev. Microbiol.
Mallmann,Carlos A.; Santurio,Janio M.; Dilkin,Paulo.
This article describes clinical, etiologic and pathologic diagnosis of an outbreak of equine leukoencephalomalacia. Two samples of the corn consumed by the affected horses contained fumonisin B1 at levels of 46 and 53 µg/g and Fusarium moniliforme, a good in vitro mycotoxin producer.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Corn; Leukoencephalomalacia; Fumonisin; Fusarium moniliforme; Chromatography.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000300011
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