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	Provedor de dados BJMBR (3) Autor Silva,I.V. (3) Meyrelles,S.S. (2) Balarini,C.M. (1) Cabral,A.M. (1) Freitas,F.P.S. (1) Gava,A.L. (1) Graceli,J.B. (1) Lopes,A.G. (1) Morales,M.M. (1) Pereira,T.M.C. (1) Vasquez,E.C. (1) Mais... Palavra-chave Aging (1) Calcium reabsorption (1) Cardiovascular disorders (1) Chloride channels (1) Dent's disease (1) Losartan (1) Nephrolithiasis (1) Nitric oxide (1) Renal function (1) Renovascular hypertension (1) Sex hormones (1) Sexual dimorphism (1) Tempol (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2011 (1) 2009 (1) 2001 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última ClC-5 chloride channel and kidney stones: what is the link? BJMBR Silva,I.V.; Morales,M.M.; Lopes,A.G.. Nephrolithiasis is one of the most common diseases in the Western world. The disease manifests itself with intensive pain, sporadic infections, and, sometimes, renal failure. The symptoms are due to the appearance of urinary stones (calculi) which are formed mainly by calcium salts. These calcium salts precipitate in the renal papillae and/or within the collecting ducts. Inherited forms of nephrolithiasis related to chromosome X (X-linked hypercalciuric nephrolithiasis or XLN) have been recently described. Hypercalciuria, nephrocalcinosis, and male predominance are the major characteristics of these diseases. The gene responsible for the XLN forms of kidney stones was cloned and characterized as a chloride channel called ClC-5. The ClC-5 chloride channel... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nephrolithiasis; Dent's disease; Calcium reabsorption; Chloride channels. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300004 Endogenous angiotensin II modulates nNOS expression in renovascular hypertension BJMBR Pereira,T.M.C.; Balarini,C.M.; Silva,I.V.; Cabral,A.M.; Vasquez,E.C.; Meyrelles,S.S.. Nitric oxide (NO) influences renal blood flow mainly as a result of neuronal nitric oxide synthase (nNOS). Nevertheless, it is unclear how nNOS expression is modulated by endogenous angiotensin II, an inhibitor of NO function. We tested the hypothesis that the angiotensin II AT1 receptor and oxidative stress mediated by NADPH oxidase contribute to the modulation of renal nNOS expression in two-kidney, one-clip (2K1C) hypertensive rats. Experiments were performed on male Wistar rats (150 to 170 g body weight) divided into 2K1C (N = 19) and sham-operated (N = 19) groups. nNOS expression in kidneys of 2K1C hypertensive rats (N = 9) was compared by Western blotting to that of 2K1C rats treated with low doses of the AT1 antagonist losartan (10 mg·kg-1·day-1; N... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitric oxide; Losartan; Tempol; Renovascular hypertension. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000700014 Gender-dependent effects of aging on the kidney BJMBR Gava,A.L.; Freitas,F.P.S.; Meyrelles,S.S.; Silva,I.V.; Graceli,J.B.. It is well known that the kidney plays an important role in the development of cardiovascular diseases such as hypertension. The normal aging process leads to changes in kidney morphology, hemodynamics and function, which increase the incidence of cardiovascular events in the elderly population. These disturbances are influenced by several factors, including gender. In general, females are protected by the effects of estrogens on the cardiorenal system. Several studies have demonstrated the beneficial effects of estrogens on renal function in the elderly; however, the relationships between androgens and kidney health during one’s lifetime are not well understood. Sex steroids have many complex actions, and the decline in their levels during aging clearly... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sexual dimorphism; Renal function; Aging; Cardiovascular disorders; Sex hormones. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900012 Registros recuperados: 3 Primeira ... 1 ... Última

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