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| Fonseca,S.F.; Mendonça,V.A.; Teles,M.C.; Ribeiro,V.G.C.; Tossige-Gomes,R.; Neves,C.D.C.; Rocha-Vieira,E.; Leite,L.H.R.; Soares,D.D.; Coimbra,C.C.; Lacerda,A.C.R.. |
| Hypertension is characterized by a pro-inflammatory status, including redox imbalance and increased levels of pro-inflammatory cytokines, which may be exacerbated after heat exposure. However, the effects of heat exposure, specifically in individuals with inflammatory chronic diseases such as hypertension, are complex and not well understood. This study compared the effects of heat exposure on plasma cytokine levels and redox status parameters in 8 hypertensive (H) and 8 normotensive (N) subjects (age: 46.5±1.3 and 45.6±1.4 years old, body mass index: 25.8±0.8 and 25.6±0.6 kg/m2, mean arterial pressure: 98.0±2.8 and 86.0±2.3 mmHg, respectively). They remained at rest in a sitting position for 10 min in a thermoneutral environment (22°C) followed by 30 min... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hypertension; Heat; Cytokines; Redox status. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000300701 |
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| Cordeiro,L.M.S.; Rabelo,P.C.R.; Moraes,M.M.; Teixeira-Coelho,F.; Coimbra,C.C.; Wanner,S.P.; Soares,D.D.. |
| Brain serotonin and dopamine are neurotransmitters related to fatigue, a feeling that leads to reduced intensity or interruption of physical exercises, thereby regulating performance. The present review aims to present advances on the understanding of fatigue, which has recently been proposed as a defense mechanism instead of a “physiological failure” in the context of prolonged (aerobic) exercises. We also present recent advances on the association between serotonin, dopamine and fatigue. Experiments with rodents, which allow direct manipulation of brain serotonin and dopamine during exercise, clearly indicate that increased serotoninergic activity reduces performance, while increased dopaminergic activity is associated with increased performance.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brain; Lethargy; Monoamines; Performance; Physical activity; Reward. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001200301 |
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