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Comparison of the human immune responses to recombinant proteins representing three distinct surface proteins of Plasmodium vivax merozoites Anais da ABC (AABC)
Cunha,Maristela Gomes da; Galinski,Mary R.; Soares,Irene S.; Souza,José Maria de; Oliveira,Salma G.; Braga,Érika; Barnwell,John W.; Rodrigues,Maurício M..
Tipo: Info:eu-repo/semantics/other
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000100016
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Importance of CD8 T cell-mediated immune response during intracellular parasitic infections and its implications for the development of effective vaccines Anais da ABC (AABC)
Rodrigues,Mauricio M.; Boscardin,Silvia B.; Vasconcelos,José R.; Hiyane,Meire I.; Salay,Gerson; Soares,Irene S..
Obligatory intracellular parasites such as Plasmodium sp, Trypanosoma cruzi, Toxoplasma gondii and Leishmania sp are responsible for the infection of hundreds of millions of individuals every year. These parasites can deliver antigens to the host cell cytoplasm that are presented through MHC class I molecules to protective CD8 T cells. The in vivo priming conditions of specific CD8 T cells during natural infection are largely unknown and remain as an area that has been poorly explored. The antiparasitic mechanisms mediated by CD8 T cells include both interferon-g-dependent and -independent pathways. The fact that CD8 T cells are potent inhibitors of parasitic development prompted many investigators to explore whether induction of these T cells can be a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CD8; Parasites; Immunity; Vaccine.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652003000400005
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São Paulo School of Advanced Sciences on Vaccines: an overview J. Venom. Anim. Toxins incl. Trop. Dis.
Sorgi,Sara; Bonezi,Vivian; Dominguez,Mariana R.; Gimenez,Alba Marina; Dobrescu,Irina; Boscardin,Silvia; Nakaya,Helder I.; Bargieri,Daniel Y.; Soares,Irene S.; Silveira,Eduardo L. V..
Abstract Two years ago, we held an exciting event entitled the São Paulo School of Advanced Sciences on Vaccines (SPSASV). Sixty-eight Ph.D. students, postdoctoral fellows and independent researchers from 37 different countries met at the Mendes Plaza Hotel located in the city of Santos, SP - Brazil to discuss the challenges and the new frontiers of vaccinology. The SPSASV provided a critical and comprehensive view of vaccine research from basics to the current state-of-the-art techniques performed worldwide. For 10 days, we discussed all the aspects of vaccine development in 36 lectures, 53 oral presentations and 2 poster sessions. At the end of the course, participants were further encouraged to present a model of a grant proposal related to vaccine...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Vaccine history; WHO priorities and challenges; Immune responses; Antigen search; Delivery systems and strategies.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100201
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