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| 豊留, 孝仁; TOYOTOME, Takahito. |
| Aspergillus species (spp.) are medically important pathogens that cause aspergillosis, and A. fumigatus is the most prevalent causative agent of the disease. Aspergillus spp. produce various secondary metabolites; however, the role of these metabolites in aspergillosis remains unclear. Gliotoxin is a major secondary metabolite produced by A. fumigatus. Several recent studies have reported that gliotoxin contributes to the virulence of A. fumigatus. Here I review studies related to gliotoxin and its contribution to the infection caused by A. fumigatus. |
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Palavras-chave: Aspergillosis; Aspergillus fumigatus; Gliotoxin; Secondary metabolite. |
| Ano: 2015 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4157 |
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