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Effect of hormone replacement on exercise cardiopulmonary reserve and recovery performance in subclinical hypothyroidism 56
Teixeira,P.F.S.; Oliveira,F.P.; Vaisman,M..
Subclinical hypothyroidism (SH) patients present cardiopulmonary, vascular and muscle dysfunction, but there is no consensus about the benefits of levothyroxine (L-T4) intervention on cardiopulmonary performance during exercise. The aim of the present study was to investigate the effects of L-T4 on cardiopulmonary exercise reserve and recovery in SH patients. Twenty-three SH women, 44 (40-50) years old, were submitted to two ergospirometry tests, with an interval of 6 months of normalization of thyroid-stimulating hormone (TSH) levels (L-T4 replacement group) or simple observation (TSH = 6.90 μIU/mL; L-T4 = 1.02 ng/dL). Patients with TSH >10 μIU/mL were excluded from the study to assure that they would receive treatment in this later stage of SH....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Subclinical hypothyroidism Thyroid dysfunction Levothyroxine; Ergospirometry Exercise physiology.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001100012
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Normal flow-mediated vasodilatation of the brachial artery and carotid artery intima-media thickness in subclinical hypothyroidism 56
Cabral,M.D.; Teixeira,P.F.S.; Silva,N.A.O.; Morais,F.F.C.; Soares,D.V.; Salles,E.; Henriques,J.M.; Leite,S.P.; Montenegro,C.A.B.; Vaisman,M..
Subclinical hypothyroidism (SHT) is a disease for which exact therapeutic approaches have not yet been established. Previous studies have suggested an association between SHT and coronary heart disease. Whether this association is related to SHT-induced changes in serum lipid levels or to endothelial dysfunction is unclear. The aim of this study was to determine endothelial function measured by the flow-mediated vasodilatation of the brachial artery and the carotid artery intima-media thickness (IMT) in a group of women with SHT compared with euthyroid subjects. Triglycerides, total cholesterol, HDL-C, LDL-C, apoprotein A (apo A), apo B, and lipoprotein(a) were also determined. Twenty-one patients with SHT (mean age: 42.4 ± 10.8 years and mean...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Subclinical hypothyroidism; Lipid profile; Endothelial function; Carotid artery intima-media thickness.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000500005
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