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| Martino,H.F.; Oliveira,P.S.; Souza,F.C.; Costa,P.C.; Assunção e Silva,E.; Villela,R.; Gaze,M.; Weitzel,L.H.; Oliveira Jr.,A.; Muccillo,F.B.; Arvelo,S.N.S.; Sá,R.; Guimarães,T.C.F.; Tura,B.R.; Campos de Carvalho,A.C.. |
| The aim of this study was to determine if bone marrow mononuclear cell (BMMC) transplantation is safe for moderate to severe idiopathic dilated cardiomyopathy (IDC). Clinical trials have shown that this procedure is safe and effective for ischemic patients, but little information is available regarding non-ischemic patients. Twenty-four patients with IDC, optimized therapy, age 46 ± 11.6 years, 17 males, NYHA classes II-IV, and left ventricular ejection fraction <35% were enrolled in the study. Clinical evaluation at baseline and 6 months after stem cell therapy to assess heart function included echocardiogram, magnetic resonance imaging, cardiopulmonary test, Minnesota Quality of Life Questionnaire, and NYHA classification. After cell transplantation 1... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bone marrow cells; Mononuclear fraction; Autologous transplantation; Ejection fraction; Treadmill test; Dilated cardiomyopathy. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001000011 |
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| Benchimol-Barbosa,P.R.; Tura,B.R.; Barbosa,E.C.; Kantharia,B.K.. |
| The SEARCH-RIO study prospectively investigated electrocardiogram (ECG)-derived variables in chronic Chagas disease (CCD) as predictors of cardiac death and new onset ventricular tachycardia (VT). Cardiac arrhythmia is a major cause of death in CCD, and electrical markers may play a significant role in risk stratification. One hundred clinically stable outpatients with CCD were enrolled in this study. They initially underwent a 12-lead resting ECG, signal-averaged ECG, and 24-h ambulatory ECG. Abnormal Q-waves, filtered QRS duration, intraventricular electrical transients (IVET), 24-h standard deviation of normal RR intervals (SDNN), and VT were assessed. Echocardiograms assessed left ventricular ejection fraction. Predictors of cardiac death and new onset... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chagas heart disease; Noninvasive electrocardiography; Prognostic score; Cardiac death; Ventricular tachycardia. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100974 |
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