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| LEAL,DALILA T.; FONTES,GLEIDE G.; VILLA,JULIA K.D.; FREITAS,RODRIGO B.; CAMPOS,MATEUS G.; CARVALHO,CAMILO A.; PIZZIOLO,VIRGINIA R.; DIAZ,MARISA A.N.. |
| Abstract: This study investigated the ability of formulation containing Zingiber officinale (ginger) to reverse health changes promoted by unhealthy diet in Wistar rats. Five compounds from the gingerol family and three from the shogaol family were identified in the chromatographic analyzes of the extract. The animals were fed a combination of unhealthy foods, the cafeteria diet, which promoted increases in body weight, hepatocyte nucleus area, total hepatocyte area and liver fat accumulation, as well as reduced hepatic glutathione S-transferase concentration, compared to the control group, which received commercial chow. The treatment with ginger improved all these results, highlighting the reduction of 10% of body weight and 66% of the total area of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cafeteria diet; Gingerol; Nonalcoholic fatty liver disease; Oxidative stress; Shogaol; Zingiber officinale. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700801 |
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