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Registros recuperados: 6
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Clinical efficacy of tirofiban combined with a Solitaire stent in treating acute ischemic stroke BJMBR
Zhang,Yang; Zhang,Qing-Qing; Fu,Cong; Wang,Lei; Zhang,Guan-Qun; Cao,Pei-Wei; Chen,Guo-Fang; Fu,Xin-Min.
This study explores the safety and effect of acute cerebral infarction treatment by microcatheter injection of tirofiban combined with a Solitaire AB stent and/or stent implantation. Emergency cerebral angiograms showing the responsible vascular occlusion of 120 acute cerebral infarction patients who underwent emergency endovascular thrombectomy were included in the study. These patients were randomly divided into two groups using the random number table method: treatment group (n=60) that received thrombectomy (with cerebral artery stents) combined with intracerebral injection of tirofiban and control group (n=60) that only received thrombectomy (with cerebral artery stents alone). The baseline data, cerebral angiography before and after surgery,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute ischemic stroke; Solitaire AB stent; Endovascular thrombectomy; Tirofiban.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001000603
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Disruption of reproductive development in male rat offspring following gestational and lactational exposure to di-(2-ethylhexyl) phthalate and genistein Biol. Res.
Zhang,Lian-Dong; Deng,Qian; Wang,Zi-Ming; Gao,Ming; Wang,Lei; Chong,Tie; Li,He-Cheng.
Studies of developmental effects of mixtures of endocrine disrupters on the male reproductive system are of great concern. In this study, the reproductive effects of the co-administration of di-2-(ethylhexyl) phthalate (DEHP) and genistein (GEN) during pregnancy and lactation were studied in male rat offspring. Pregnant Sprague-Dawley rats were gavaged from gestation day 3 to postnatal day 21 with vehicle control, DEHP 250 mg/kg body weight (bwyday, GEN 50 mg/kg bwday, GEN 400 mg/kg bwday, and two combinations of the two compounds (DEHP 250 mg/kg bwday + GEN 50 mg/kg bwday, DEHP 250 mg/kg bwday + GEN 400 mg/kg bwday). The outcomes studied were general morphometry (weight, AGD), testicular histology, testosterone levels, and expression at the mRNA level of...
Tipo: Journal article Palavras-chave: Di-2-(ethylhexyl) phthalate; Genistein; Pregnancy; Lactation; Reproductive system.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000200004
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Effect of probiotic Lactobacillus reuteri XC1 coexpressing endoglucanase and phytase on intestinal pH and morphology, carcass characteristics, meat quality, and serum biochemical indexes of broiler chickens R. Bras. Zootec.
Wang,Lei; Feng,Yuzhe; Zhang,Xiaowei; Wu,Guofang.
ABSTRACT This study investigated the effect of transformed Lactobacillys reuteri on intestinal pH and morphology, carcass characteristics, meat quality, and serum biochemical indexes of broiler chickens. A total of 480 broilers were assigned to six treatment groups and fed a phosphorus-adequate diet, a phosphorus-deficient diet, or a phosphorus-deficient diet containing different L. reuteri recombinants. The results showed that transformed L. reuteri decreased the pH in the duodenum and jejunum of chickens at day 21, decreased drip loss and cooking loss of muscles, and improved muscle tenderness of chickens at days 21 and 42, but did not affect carcass characteristics and only slightly decreased abdominal fat. Transformed L. reuteri also significantly...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bird nutrition; Meat quality; Microbial additive; Phosphorus; PH; Villus.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982019000100519
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Effects and molecular mechanism of chitosan-coated levodopa nanoliposomes on behavior of dyskinesia rats Biol. Res.
Cao,Xuebing; Hou,Dongzhi; Wang,Lei; Li,Sai; Sun,Shengang; Ping,Qineng; Xu,Yan.
BACKGROUND: Chitosan, the N-deacetylated derivative of chitin, is a cationic polyelectrolyte due to the presence of amino groups, one of the few occurring in nature. The use of chitosan in protein and drug delivery systems is being actively researched and reported in the literature RESULTS: In this study, we used chitosan-coated levodopa liposomes to investigate the behavioral character and the expression of phosphorylated extracellular signal-regulated kinase (ERK1/2), dopamine- and cAMP-regulated phos-phoprotein of 32 kDa (DARPP-32) and FosB/AFosB in striatum of rat model of levodopa-induced dyskinesia (LID). We found that scores of abnormal involuntary movement (AIM) decreased significantly in liposome group (P < 0.05), compared with levodopa group....
Tipo: Journal article Palavras-chave: Dyskinesia; Levodopa liposomes; ERK1/2; DARPP-32; FosB/AFosB.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100032
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Morphological study of the gastrointestinal tract of Larimichthys crocea (Acanthopterygii: Perciformes) Rev. Bras. Zool.
Kalhoro,Hameeda; Tong,Shengli; Wang,Lei; Hua,Ying; Volatiana,Josie Ancella; Shao,Qingjun.
ABSTRACT The present study aimed to investigate the macroscopic and histological structure of the gastrointestinal tract (GIT) of Larimichthys crocea (Richardson, 1846). It consists of esophagus, stomach regions, pyloric caeca, intestinal regions, and rectum. Sixteen tubular light yellowish pyloric caeca of similar sizes were observed in all individuals. The digestive wall consists of mucosa, submucosa, muscularis, and adventitia. No major differences appeared in the structure of the tunica, epithelial cell types, connective tissues and musculature glands of L. crocea GIT. The mucosal epithelia in the oesophagus has longitudinal branched folds with frontward and hindmost zones. The gastric tunica mucosa has a characteristic folded structure and can be...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anatomy; Epithelial mucins; Gastrointestinal tract; Intestinal coefficient; Large yellow croaker.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702018000100342
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Use of green fluorescent protein to monitor Lactobacillus plantarum in the gastrointestinal tract of goats BJM
Han,Xufeng; Wang,Lei; Li,Wei; Li,Bibo; Yang,Yuxin; Yan,Hailong; Qu,Lei; Chen,Yulin.
The experiment aimed to specifically monitor the passage of lactobacilli in vivo after oral administration. The green fluorescent protein (GFP) gene was cloned downstream from the constitutive p32 promoter from L. lactis subsp. cremoris Wg2. The recombinant expression vector, pLEM415-gfp-p32, was electroporated into Lactobacillus plantarum (L. plantarum) isolated from goat. Green fluorescent protein (GFP) was successfully expressed in L. plantarum. After 2 h post-administration, transformed Lactobacillus could be detectable in all luminal contents. In the rumen, bacteria concentration initially decreased, reached the minimum at 42 h post-oral administration and then increased. However, this concentration decreased constantly in the duodenum. This result...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Green fluorescent protein; Gastro-intestinal tract; Lactobacillus plantarum; Goat.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000300849
Registros recuperados: 6
Primeira ... 1 ... Última
 

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