Sabiia Seb
PortuguêsEspañolEnglish
Embrapa
        Busca avançada

Botão Atualizar


Botão Atualizar

Ordenar por: RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 11
Primeira ... 1 ... Última
Imagem não selecionada

Imprime registro no formato completo
Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles. Repositório Alice
BIGI, M.; VAZQUEZ, C. L.; CASTELÃO, A. B. C.; GARCÍA, E. A.; CATALDI, A. A.; JACKSON, M.; MAcNEIL, M.; SORIA, M.; ZUMÁRRAGA, M. J.; MATIAS, C.; GAGO, G.; BLANCO, F. C.; NISHIBEF, C.; ALMEIDA, N. F.; ARAUJO, F. R.; BIGI, F..
Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic losses worldwide. Two M. bovis strains (04-303 and 534) have been isolated in Argentina. Whereas the 04-303 strain was isolated from a wild boar, the 534 strain was obtained from cattle. In a previous study, six weeks after infection, the 04-303 strain induced 100% mortality in mice. By contrast, mice infected with the 534 strain survived, with limited tissue damage, after four months. In this study we compared all predictive proteins encoded in both M. bovis genomes. The comparative analysis revealed 141 polymorphic proteins between...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Mutations; Gene; Mycobacterium bovis BCG; Genome; Virulence.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1117921
Imagem não selecionada

Imprime registro no formato completo
Comparação de genes de virulência de duas cepas de Mycobacterium bovis com perfis patogênicos contrastantes. Infoteca-e
CASTELÃO, A. B. C.; NISHIBE, C.; ZUMÁRRAGA, M. J.; CATALDI, A.; BIGI, F.; RAMOS, C. A. do N.; ALMEIDA, V. F.; ARAUJO, F. R..
2015
Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) Palavras-chave: Mycobacterium bovis; Genes de virulência; Genoma.
Ano: 2015 URL: http://www.infoteca.cnptia.embrapa.br/handle/doc/1026502
Imagem não selecionada

Imprime registro no formato completo
Diagnostic tools to detect pathogens causing tuberculosis in cattle and prevent their transmission through dairy products to humans. Repositório Alice
ARAUJO, F. R.; ALMEIDA, N. F.; ZUMÁRRAGA, M. J..
2016
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Leite; Tuberculose; Cattle; Tuberculosis; Dairy.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1066274
Imagem não selecionada

Imprime registro no formato completo
Draft Genome Sequence of Mycobacterium bovis 04-303, a Highly Virulent Strain from Argentina. Repositório Alice
NISHIBE, C.; CASTELÃO, A. B. C.; COSTA, R. D.; PINTO, B. J.; VARUZZA, L.; CATALDI, A. A.; BERNARDELLI, A.; BIGI, F.; BLANCO, F. C.; ZUMÁRRAGA, M. J.; ALMEIDA, N. F.; ARAUJO, F. R..
2013
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Mycobacterium bovis.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/980151
Imagem não selecionada

Imprime registro no formato completo
Epidemiological Study of Mycobacterium bovis Infection in Buffalo and Cattle in Amazonas, Brazil. Repositório Alice
CARNEIRO, P. A. M.; TAKATANI, H.; PASQUATTI, T. N.; SILVA, C. B. D. G.; NORBY, B.; WILKINS, M. J.; ZUMÁRRAGA, M. J.; ARAUJO, F. R.; KANEENE, J. B..
Bovine Tuberculosis (BTB) is an endemic disease in about one hundred countries, affecting the economy causing a decrease in productivity, condemnation of meat, and damaging the credibility on international trade. Additionally, Mycobacterium bovis the major causative agent for BTB can also infect humans causing a variety of clinical presentations. The aim of this study was to determine BTB prevalence and the main risk factors for theMycobacterium bovis prevalence in cattle and buffalos in Amazonas State, Brazil. Tissue samples from 151 animals (45 buffalo and 106 cattle from five herds with buffalo only, 22 herds with cattle only, and 12 herds with buffalo and cattle) were obtained from slaughterhouses under State Veterinary Inspection. M. bovis were...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Bovine tuberculosis; Mycobacterium bovis BCG; Cattle; Buffaloes; Epidemiology.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1117948
Imagem não selecionada

Imprime registro no formato completo
Identificação e genotipagem de Mycobacterium bovis em bovinos positivos no teste intradérmico para tuberculose em Mato Grosso do Sul1. Repositório Alice
CAZOLA, D de O.; JORGE, K. dos S. G.; ZUMÁRRAGA, M. J.; SOUZA-FILHO, A. F.; ARAUJO, F. R.; OSÓRIO, A. L. A. R..
Neste estudo, realizou-se genotipagem de isolados de Mycobacterium bovis, provenientes de amostras de tecidos de bovinos positivos no teste cervical comparativo (TCC) para tuberculose em Mato Grosso do Sul, por meio da técnica de spoligotyping.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Mycobacterium bovis; Molecular identification; Molecular epidemiology; Poligotyping; Bovine tuberculosis.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1015208
Imagem não selecionada

Imprime registro no formato completo
Matrix Assisted Laser Desorption Ionization-Time-of-Flight mass spectrometry identification of Mycobacterium bovis in Bovinae. Repositório Alice
BACANELLI, G.; OLARTE, L. C.; SILVA, M. R.; RODRIGUES, R. A.; CARNEIRO, P. A. M.; KANEENE, J. B.; PASQUATTI, T. N.; TAKATANI, H.; ZUMÁRRAGA, M. J.; ETGES, R. N.; ARAUJO, F. R.; VERBISCK, N. V..
In this study, Matrix Assisted Laser Desorption Ionization-Time-of-Flight (MALDITOF) mass spectrometry was used to identify Mycobacterium bovis from cattle and buffalo tissue isolates from the North and South regions of Brazil, grown in solid medium and previously identified by Polymerase Chain Reaction (PCR) based on Region of Difference 4 (RD4), sequencing and spoligotyping. For this purpose, the protein extraction protocol and the mass spectra reference database were optimized for the identification of 80 clinical isolates of mycobacteria. As a result of this optimization, it was possible to identify and differentiate M. bovis from other members of the Mycobacterium tuberculosis complex with 100% specificity, 90.91% sensitivity and 91.25% reliability....
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Matrix Assisted Laser Desorption Ionization-Time-of-Flight (MALDI-TOF) mass spectrometry; Bovine tuberculosis; Mycobacterium bovis BCG; Mycobacterium tuberculosis complex.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1117863
Imagem não selecionada

Imprime registro no formato completo
Molecular characterization of Mycobacterium bovis infection in cattle and buffalo in Amazon Region, Brazil. Repositório Alice
CARNEIRO, P. A. M.; PASQUATTI, T. N.; TAKATANI, H.; ZUMÁRRAGA, M. J.; MARFIL, M. J.; BARNARD, C.; FITZGERALD, S. D.; ABRAMOVITCH, R. B.; ARAUJO, F. R.; KANEEENE, J. B..
The aim of this study was to characterize Mycobacterium bovis from cattle and buffalo tissue samples, from two Brazilian states, and to analyse their genetic diversity by spoligotyping. Tissue samples from tuberculosis suspect animals, 57 in Amazonas State (12 cattle and 45 buffaloes) and six from Pará State (5 cattle and one buffalo) from slaughterhouses under State Veterinary Inspection, were isolated in culture medium Stonebrink. The positive cultures were confirmed by PCR and analysed by the spoligotyping technique and the patterns (spoligotypes) were identified and compared at the Mycobacterium bovis Spoligotype Database (http://www.mbovis.org/). There was bacterial growth in 44 (69.8%) of the tissues of the 63 animals, of which PCR for region of...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Cattle and buffalo; Genotypes; Spoligotyping; Mycobacterium Bovis; Bovine tuberculosis; Mycobacterium bovis BCG.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1117813
Imagem não selecionada

Imprime registro no formato completo
Patterns and Processes of Mycobacterium bovis Evolution Revealed by Phylogenomic Analyses. Repositório Alice
PATANE, J. S. L.; MARTINS JUNIOR, J.; CASTELÃO, A. B.; NISHIBE, C.; MONTERA, L.; BIGI, F.; ZUMÁRRAGA, M. J.; CATALDI, A. A.; FONSECA JUNIOR, A.; ROXO, E.; OSÓRIO, A. L. A. R.; JORNGE, K. S.; THACKER, T. C.; ALMEIDA, N. F.; ARAUJO, F. R.; SETUBAL, J. C..
Mycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South Korea, Brazil, and the United States revealed four novel large-scale structural variations of at least 2,000 bp.Acomparative phylogenomic study including 2,483 core genes of 38 taxa from eight countries showed conflicting phylogenetic signal among sites. By minimizing this effect,we obtained a tree that better agreeswith sampling locality. Results supported a relatively basal position of African strains (all isolated from Homo sapiens), confirming that Africa was an important region for early diversification and that humans were one of...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Phylogenomics; Tuberculose bovina; Filogenômica; Família PE / PPE; Mycobacterium bovis; Epidemiologia; Mycobacterium bovis; Bovine tuberculosis.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1077365
Imagem não selecionada

Imprime registro no formato completo
Polymorphisms of 20 regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis. Repositório Alice
BIGI, M. M.; BLANCO, F. C.; ARAUJO, F. R.; THACKER, T. C.; ZUMÁRRAGA, M. J.; CATALDI, A. A.; SORIA, M. A.; BIGI, F..
Mycobacterium tuberculosis and Mycobacterium bovis are responsible for tuberculosis in humans and animals, respectively. Both species are closely related and belong to the Mycobacterium tuberculosis complex (MTC). M. tuberculosis is the most ancient species from which M. bovis and other members of the MTCevolved. The genome of M. bovis is over>99.95% identical to that of M. tuberculosis but with seven deletions ranging in size from 1 to 12.7 kb. In addition, 1200 single nucleotide mutations in coding regions distinguish M. bovis from M. tuberculosis. In the present study, we assessed 75 M. tuberculosis genomes and 23 M. bovis genomes to identify non-synonymous mutations in 202 coding sequences of regulatory genes between both species. We identified...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Regulator; Mycobacterium bovis; Polimorfismo; Anoxia; Mycobacterium bovis; Mycobacterium tuberculosis; Polymorphism.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1087980
Imagem não selecionada

Imprime registro no formato completo
Population structure, genotypes and pathogenic phenotype of Mycobacterium bovis in Argentina (and Latin America). Repositório Alice
ZUMÁRRAGA, M. J.; ARAUJO, F. R..
2015
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Bovine tuberculosis; Mycobacterium bovis; Spoligotyping; Clusters.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1012228
Registros recuperados: 11
Primeira ... 1 ... Última
 

Empresa Brasileira de Pesquisa Agropecuária - Embrapa
Todos os direitos reservados, conforme Lei n° 9.610
Política de Privacidade
Área restrita

Embrapa
Parque Estação Biológica - PqEB s/n°
Brasília, DF - Brasil - CEP 70770-901
Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco

Valid HTML 4.01 Transitional