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Leptin and adiponectin in the female life course BJMBR
Lecke,S.B.; Morsch,D.M.; Spritzer,P.M..
Adipose tissue secretes a variety of adipokines, including leptin and adiponectin, which are involved in endocrine processes regulating glucose and fatty metabolism, energy expenditure, inflammatory response, immunity, cardiovascular function, and reproduction. The present article describes the fluctuations in circulating leptin and adiponectin as well as their patterns of secretion in women from birth to menopause. During pregnancy, leptin and adiponectin seem to act in an autocrine/paracrine fashion in the placenta and adipose tissue, playing a role in the maternal-fetal interface and contributing to glucose metabolism and fetal development. In newborns, adiponectin levels are two to three times higher than in adults. Full-term newborns have...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Female; Adiposity; Leptin; Adiponectin.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000500001
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P wave dispersion in obese dogs with and without mitral valve disease Ciência Rural
Dittrich,Gustavo; Campos,Gabriela Marin Van der Broocke; Sousa,Marlos Gonçalves; Oliveira,Simone Tostes.
ABSTRACT: Pwave dispersion (Pd) is an electrocardiographic index defined as the difference between the minimum and maximum Pwave duration in multiple leads. The augmentation of Pd reflects the discontinuous and inhomogeneous atrial depolarization resulting from cardiac and non-cardiac conditions. In humans, an increased Pd is associated with the development of cardiac arrhythmias, particularly atrial fibrillation. To investigate Pd in obese dogs, we enrolled 76 dogs, which were classified in four distinct categories according to body condition and the existance of valve insufficiency: obese dogs (O), dogs with both obesity and cardiac disease (O+CD), lean dogs with cardiac disease (CD) and healthy controls (H). To be included in the study, all dogs...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mitral degeneration; P wave indices; Adiposity; Obesity; Left atrial size.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000602
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Pros and cons of insulin administration on liver glucose metabolism in strength-trained healthy mice BJMBR
Pereira,V.A.R.; Vedovelli,K.S.; Muller,G.Y.; Depieri,Y.F.; Avelar,D.H.C.G.; de Amo,A.H.E.; Jimenes,D.R.; Martins,J.N.L.; Silvério,A.C.; Gomes,C.R.G.; Godoi,V.A.F.; Pedrosa,M.M.D..
Non-diabetic individuals use hormones like insulin to improve muscle strength and performance. However, as insulin also leads the liver and the adipose tissue to an anabolic state, the purpose of this study was to investigate the effects of insulin on liver metabolism in trained non-diabetic Swiss mice. The mice were divided into four groups: sedentary treated with saline (SS) or insulin (SI) and trained treated with saline (TS) or insulin (TI). Training was made in a vertical stair, at 90% of the maximum load, three times per week. Insulin (0.3 U/kg body weight) or saline were given intraperitoneally five times per week. After eight weeks, tissue and blood were collected and in situ liver perfusion with glycerol+lactate or alanine+glutamine (4 mM each)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Muscle strength; Gluconeogenesis; Liver; Adiposity; Training.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000200605
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