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Registros recuperados: 36
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A simple mathematical model to determine the ideal empirical antibiotic therapy for bacteremic patients BJID
Tuon,Felipe F.; Rocha,Jaime L.; Leite,Talita M.; Dias,Camila.
BACKGROUND: Local epidemiological data are always helpful when choosing the best antibiotic regimen, but it is more complex than it seems as it may require the analysis of multiple combinations. The aim of this study was to demonstrate a simplified mathematical calculation to determine the most appropriate antibiotic combination in a scenario where monotherapy is doomed to failure. METHODS: The susceptibility pattern of 11 antibiotics from 216 positive blood cultures from January 2012 to January 2013 was analyzed based on local policy. The length of hospitalization before bacteremia and the unit (ward or intensive care unit) were the analyzed variables. Bacteremia was classified as early, intermediate or late. The antibiotics were combined according to the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mathematical model; Infection; Antibiotic; Bacteremia.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400360
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Antagonistic activity of antibiotic producing Streptomyces sp. against fish and human pathogenic bacteria BABT
Hossain,Nazmul; Rahman,Mahbubur.
In this study, attempts were made to isolate Streptomyces sp. from soil samples of two different regions of Bangladesh and evaluate their antagonistic activity against fish and human pathogenic bacteria. A total of 10 isolates were identified as Streptomyces sp. based on several morphological, physiological and biochemical tests. Cross streak method was used to observe the antagonistic activity of the Streptomyces sp. isolates against different fish pathogens belonging to the genus Aeromonas, Pseudomonas and Edwardsiella and human clinical isolates belonging to the genus Klebsiella, Salmonella and Streptococcus. Seven Streptomyces sp. isolates showed antagonism against both fish and human pathogenic bacteria. Four isolates viz., N24, N26, N28 and N47...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptomyces sp.; Antagonistic activity; Cross streak method; Antibiotic.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000200011
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Antibacterial activity of propolis produced by Frieseomelitta varia Ciência e Agrotecnologia
Campos,Viviane Aparecida Costa; Santos Júnior,Helvécio Martins dos; Oliveira,Denilson F; Carvalho,Hudson Walace Pereira de; Machado,Alan Rodrigues Teixeira; Tirelli,Aline Auxiliadora.
To contribute to the development of antibacterial products from propolis produced by native Brazilian bees, twenty-nine samples of propolis collected from hives in the state of Minas Gerais, Brazil, were screened for in vitro activity against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. Among the samples from native Brazilian bees, only that from Frieseomelitta varia (Lepeletier, 1836) inhibited in vitro bacterial growth. Consequently, this propolis underwent fractionation by chromatographic methods monitored through Agar-diffusion assays with these bacteria, which resulted in the isolation and identification of 3,5-diprenyl-4-hydroxycinnamic acid (artepillin C), which showed MIC of 62.5 and 250 µg/mL against...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Artepillin C; Stingless bees; Antibiotic.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542011000600002
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Antibacterial and cytotoxicity activity in macroalgae extracts: perspectives for the use against pathogenic bacteria from shrimp farms (Litopenaeus vannamei) Biological Sciences
Silva, Giselle Cristina; Soares, Raquel Cavalcante; Carvalho, Fátima Cristiane Teles; Rocha, Rafael dos Santos; Vieira, Regine Helena Silva dos Fernandes; Sousa, Oscarina Viana de.
Some infections caused by pathogenic microorganisms might shows high prevalence in farmed shrimp environments, compromising production and causing economic losses. Therefore, the search for compounds with antibiotic activity has become intensive, following the record of new antimicrobial-resistant bacteria. The study of those bioactive compounds in marine macroalgae has produced satisfactory results, such as the discovery of antibacterial activity against multiresistant strains. Accordingly, this study aims to research antibiotic activity in macroalgae extracts of Chlorophyta, Phaeophyta and Rhodophyta found in the coast of Ceará and also to evaluate the cytotoxicity activity against bacterial strains (Vibrio sp.) from shrimp farms (Litopenaeus vannamei)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: 2.12.02.00-1 bioactivity; Antibiotic; Cytotoxicity; Resistance. Microbiologia Aplicada.
Ano: 2018 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/40053
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Antibiotic residues in pasteurized and unpasteurized milk marketed in southwest of Paraná, Brazil Ciência Rural
Schlemper,Valfredo; Sachet,Ana Paula.
ABSTRACT: The treatment of dairy cattle with antibiotics may lead to milk contamination by drugs residues, which represents risks to human health. This study aimed to investigate the presence of antibiotic residues in milk, produced and marketed in Capanema microregion, Paraná, Brazil, through the analysis of pasteurized milk samples from different brands consumed by the local population and unpasteurized milk samples provided by a dairy industry. Enzyme immunoassays screening kits SNAPduo™ Beta-Tetra ST Test (Idexx Laboratories) were used, which verified the presence of β-lactam and tetracyclic drugs residues, as well as enzyme immunoassays screening kits Charm ROSA Test (Charm Sciences), which established the presence of quinolones and sulfonamides...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibiotic; Milk quality; Public health; Food safety; Pasteurization.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001200451
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Antimicrobial and anti-inflammatory activities of Apis mellifera honey on the Helicobacter pylori infection of Wistar rats gastric mucosa Ciênc. Tecnol. Aliment.
AMARAL,Thiago Yamamoto; PADILHA,Igor Gomes; PRESÍDIO,Gustavo Alvares; SILVEIRA,Edmo Arruda Aguiar Sobreira da; DUARTE,Alysson Wagner Fernandes; BARBOSA,Ana Paula Fernandes; BEZERRA,Antônio Fernando de Souza; LÓPEZ,Ana Maria Queijeiro.
Abstract Considering that Helicobacter pylori, a bacterium able to colonize the upper gastrointestinal tract and cause mucosal injury, not always can be effectively eradicated by the traditional approaches, there is an interest in alternative therapies until a vaccine be available. Honey is a food supplement with high carbohydrate content and antioxidant activity, as well as broad antimicrobial spectrum. After analyzing the physicochemical and in vitro antimicrobial properties of an Apis mellifera honey from the Atlantic forest of Alagoas / Brazil, the purpose of the present work was evaluate its in vivo effects against Helicobacter pylori in the gastric mucosa of Wistar rats. First, it was verified the success of inoculation/infection of the pathogen in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gastritis; Peptic ulcer; Antioxidant; Anti-inflammatories; Antibiotic.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612017000500034
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Antimicrobial susceptibility of Clostridium perfringens isolated from piglets with or without diarrhea in Brazil BJM
Salvarani,Felipe Masiero; Silva,Rodrigo Otávio Silveira; Pires,Prhiscylla Sadanã; Cruz Júnior,Eduardo Coulaud da Costa; Albefaro,Isabella Silva; Guedes,Roberto Maurício de Carvalho; Lobato,Francisco Carlos Faria.
The minimum inhibitory concentration (MIC) was determined for 13 antibiotics against Clostridium perfringens isolated from Brazilian piglets. The collection of isolates was performed in June to October 2010. All isolates were susceptible to amoxicillin and ceftiofur, whereas most were resistant to tetracycline and lincomycin. Avilamycin and narasin were more effective against isolates from non-diarrheic than from diarrheic piglets. The other antimicrobials were less active in need of high concentrations to inhibit the growth of the C. perfringens type A. These results suggest the need for further studies evaluating molecular factors related to the antimicrobial resistance of C. perfringens.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Clostridium perfringens; Piglet; Diarrhea; Antibiotic.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300027
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Antimycobacterial activity of a Brevibacillus Laterosporus strain isolated from a moroccan soil BJM
Hassi,Mohammed; El Guendouzi,Souraya; Haggoud,Abdelleatif; David,Susana; Ibnsouda,Saad; Houari,Abdellah; Iraqui,Mohammed.
The treatment of tuberculosis has become more difficult with the worldwide spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis. Moreover, the prevalence of human disease caused by atypical mycobacteria has also increased in the past two decades and has further complicated the problem of the treatment of mycobacterial infections. It is therefore urgent to develop new highly active molecules against these bacteria. The present study reports the isolation from a Moroccan soil of a Bacillus strain that exhibits an important antimycobacterial activity. The strain was identified as Brevibacillus laterosporus using DNA sequencing of the 16S ribosomal RNA gene. The antimycobacterial activity was assigned...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mycobacteria; Antimycobacterial; Antibiotic; Brevibacillus.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400036
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Application of the antibiotic disk diffusion method to multivariate profiling of soil bacterial community: comparing the power to discriminate different soils and dimension of the discrimination with that of the Biolog method BJM
Doi,Ryoichi.
The antibiotic disk diffution (ADD) method was compared with the Biolog method in terms of power to discriminate soils and dimension of the discrimination. Soils from a forest and a citrus field in Thailand were profiled with these methods. These methods differentiated the soils in the principal component score plots. Then, Wilk's lambda statistic was determined to estimate power of these methods to discriminate the soils. The ADD method scored Wilk's lambda of 0.003 (p = 0.144) and 0.000 (p=0.020), for direct and ratio-transformed calculation, respectively. The Biolog method recorded Wilk's lambda of 0.001 (p=0.067), 0.003 (p=0.144) and 0.035 (p=0.440), at 0.25, 0.50 and 0.75 average well color developments (AWCDs), respectively. The ADD method showed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibiotic; Biolog; Disk diffusion; Soil microbial community.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000400005
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Assessment of cowpea rhizobium diversity in Cerrado areas of northeastern Brazil BJM
Zilli,Jerri Édson; Valisheski,Romano Roberto; Freire Filho,Francisco Rodrigues; Neves,Maria Cristina Prata; Rumjanek,Norma Gouvêa.
In order to contribute for the optimization of biological nitrogen fixation (BNF) associated with cowpea in Cerrado areas in the Northeast region of Brazil, this work aimed to analyze the diversity of rhizobial populations in eight areas of Cerrado, during a soybean and rice-cowpea rotation. Morphological traits (mucous production and colony morphology), genotypic analyzes (ARDRA 16S) and intrinsic resistance to antibiotics were determined for a collection of isolates captured using cowpea as a host-plant. The morphological data showed a inverse correlation (p < 0.05) between the number of legume (soybean and cowpea) crops, according to the history of each area, and rhizobium diversity, estimated by the Shannon-Weaver index. ARDRA data showed that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diversity; Bradyrhizobium; Cerrado; Cowpea; Antibiotic.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822004000300002
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Bacteriocins: exploring alternatives to antibiotics in mastitis treatment BJM
Pieterse,Reneé; Todorov,Svetoslav D..
Mastitis is considered to be the most costly disease affecting the dairy industry. Management strategies involve the extensive use of antibiotics to treat and prevent this disease. Prophylactic dosages of antibiotics used in mastitis control programmes could select for strains with resistance to antibiotics. In addition, a strong drive towards reducing antibiotic residues in animal food products has lead to research in finding alternative antimicrobial agents. In this review we have focus on the pathogenesis of the mastitis in dairy cows, existing antibiotic treatments and possible alternative for application of bacteriocins from lactic acid bacteria in the treatment and prevention of this disease.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mastitis; Antibiotic; Milk; Bacteriocin; Food safety.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300003
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Bioactive fractions from cantabrian anchovy (Engraulis encrarischolus) viscera Ciênc. Tecnol. Aliment.
BURGOS-HERNÁNDEZ,Armando; ROSAS-BURGOS,Ema-Carina; MARTÍNEZ,Marina; NUNCIO-JAUREGUI,Paloma-Nallely; MARHUENDA,Frutos; KAČÁNIOVÁ,Miroslava; PETROVÁ,Jana; CARBONELL-BARRACHINA,Angel-Antonio.
Abstract The potential of cantabrian anchovy (Engraulis encrarischolus) viscera as a source of bioactive compounds is of interest for both, pharmaceutical and food industries. Cantabrian anchovy guts and heads were freeze-dried, extracted with methanol and subjected to fractionation by solvent partitioning using hexane, ethyl acetate, and butanol. Fractions were tested for antimutagenic, antioxidant, antifungal, and antibacterial activity using the Ames test; DPPH, ABTS, and FRAP assays; the radial grown inhibition assay; and the microbroth dilution method, respectively. Five fractions were obtained from the anchovy gut methanolic extract, in addition to the hexane- (HF), ethyl acetate- (EAF), and butanol-soluble (BF) fractions, an aqueous-soluble fraction...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimutagenicity; Antibiotic; Antioxidant; Fungistatic; Anchovy gut.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612016000300426
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Climate conditions associated with the occurrence of antimicrobial and macrocyclic lactone residues in bulk tank milk Arq. Bras. Med. Vet. Zootec.
Picinin,L.C.A.; Toaldo,I.M.; Hoff,R.B.; Souza,F.N.; Leite,M.O.; Fonseca,L.M.; Diniz,S.A.; Silva,M.X.; Haddad,J.P.A.; Cerqueira,M.M.O.P.; Bordignon-Luiz,M.T..
ABSTRACT The present study aimed to identify the climate condition parameters that are associated with the occurrence of antimicrobial and macrocyclic lactone residues in bulk tank milk using a multivariate principal components analysis (PCA). A total of 132 raw milk samples were collected at dairy farms in Minas Gerais State in Brazil and analyzed for 35 analytes, comprising macrocyclic lactones and antibacterials, using liquid chromatography coupled with mass spectrometry in tandem mode spectrometry. Of the 132 samples, 34 (25.76%) bulk tank milk samples were positive for at least one analyte. PCA showed that antimicrobial residues in bulk tank milk occurred less frequently on days with a higher average temperature, maximum temperature and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anthelmintic; Antibiotic; Veterinary drug; Seasonality; Raw milk.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000200474
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Comparative Effect of The Inclusion of Zootechnical Additives in the Feed of Japanese Quails in Two Productive Phases Anais da ABC (AABC)
LEMOS,MARINA J.; CALIXTO,LÍGIA F.L.; SOUZA,DANIELE S.; REIS,TÚLIO L.; NASCIMENTO,APARECIDA A.; OLIVEIRA,CARLOS A..
Abstract This study aimed to evaluate the intestinal morphology, performance and financial analysis of the inclusion of additives in the feed during the productive period of 360 Japanese quails distributed in a completely randomized design in a split plot scheme in time with five treatments and eight repetitions of nine birds each. The treatments were: control, antibiotic, prebiotic, probiotic and synbiotic. The variables were: height, width and width/height ratio of the villi, crypt depth and villus/crypt ratio, feed intake, egg production, egg weight average, egg mass, feed conversion per mass and per dozen eggs and viability, internal rate of return, net present value and cost benefit. The additives in the feed increased height and width of the villi,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibiotic; Intestinal morphology; Prebiotic; Probiotic; Symbiotic.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000703313
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Conjunctival endogenous microbiota in patients submitted to cataract surgery BJM
Locatelli,Claudete I.; Kwitko,Sérgio; Simonetti,Amauri Braga.
Bacterial isolation, identification and antimicrobial susceptibility tests were carried out in ocular material collected with swab and polimethylmethacrylate (PMMA) or silicone intraocular lenses (IOL) from forty six patients submitted to cataract surgery. Seventy six isolates and seven different microorganisms were identified. Coagulase-negative staphylococci (CNS) were the predominant microorganisms isolated from swabs (71.4% of cases), PMMA lenses (81.3%) and silicon lenses (77.8%). Coagulase-negative staphylococci isolates revealed high resistance to penicillin G followed by tetracycline, chloramphenicol and aminoglicosides. However, these isolates displayed great susceptibility to vancomycin, cephalothin and ofloxacin. Except for penicillin G,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteria; Conjunctiva; Cataract; Intraocular lens; Antibiotic.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000300004
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Economic Impact of a Ban on the Use of Over-the-Counter Antibiotics in U.S. Swine Rations AgEcon
Hayes, Dermot J.; Jensen, Helen H.; Backstrom, Lennart; Fabiosa, Jacinto F..
Antibiotic drugs are currently used in 90 percent of starter feeds, 75 percent of grower feeds, more than 50 percent of finishing feeds and at least 20 percent of sow feeds (USDA/APHIS). A ban on the use of feed-grade antibiotics would lead to changes in production processes and practices in production of pork, and hence would have an economic impact on the U.S. pork industry and pork market. This study considers the economic effects of a ban in pork production, with no change of regulation on other meats. The analysis uses a set of technical assumptions that are based in large part on a historical analysis of how the Swedish ban influenced the Swedish pork industry to anticipate the potential economic effects. A range of cases is examined. The cases use...
Tipo: Working or Discussion Paper Palavras-chave: Antibiotic; Ban; Economic impact; Finishing feeds; Grower feeds; Hog farms; Over-the-counter; Pork industry; Pork market; Sow; Starter feeds; Livestock Production/Industries.
Ano: 1999 URL: http://purl.umn.edu/18667
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Efectividad in vitro de cepas nativas de Trichoderma spp. En aislados de Phytophthora parasítica D. Obtenidos de plantas de jamaica Colegio de Postgraduados
Esparza Luna, Linda Luz.
Se aislaron cepas nativas de Trichoderma spp. y Phytophthora parasitica en suelos cultivados con jamaica y con alta incidencia de la enfermedad “pata prieta de la jamaica”. La toma de muestras de suelo se ubicó en los municipios de Tecoanapa, Ayutla de los Libres, San Marcos y Juan R. Escudero del estado de Guerrero. Las cepas patogénicas se aislaron de tallo y raíz enfermo con síntomas evidentes de “pata prieta”. Trichoderma spp. se aisló directamente de suelo mediante el método de dilución de esporas en cajas Petri con el medio de cultivo Papa dextrosa agar. Se obtuvieron tres cepas de P. parasitica y 15 cepas de Trichoderma, correspondiendo a las siguientes especies, 8 a T. asperellum, 3 a T. harzianum, 1 a T. virens, 1 a T. inhamatum, 1 a...
Tipo: Tesis Palavras-chave: Antagonismo; Antibiosis; Trichoderma spp; Phytophthora parasitica; Jamaica; Maestría; Fitopatología; Antangonism; Antibiotic; Jamaica.
Ano: 2009 URL: http://hdl.handle.net/10521/1357
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Efectividad in vitro de cepas nativas de Trichoderma spp. En aislados de Phytophthora parasítica D. Obtenidos de plantas de jamaica Colegio de Postgraduados
Esparza Luna, Linda Luz.
Se aislaron cepas nativas de Trichoderma spp. y Phytophthora parasitica en suelos cultivados con jamaica y con alta incidencia de la enfermedad “pata prieta de la jamaica”. La toma de muestras de suelo se ubicó en los municipios de Tecoanapa, Ayutla de los Libres, San Marcos y Juan R. Escudero del estado de Guerrero. Las cepas patogénicas se aislaron de tallo y raíz enfermo con síntomas evidentes de “pata prieta”. Trichoderma spp. se aisló directamente de suelo mediante el método de dilución de esporas en cajas Petri con el medio de cultivo Papa dextrosa agar. Se obtuvieron tres cepas de P. parasitica y 15 cepas de Trichoderma, correspondiendo a las siguientes especies, 8 a T. asperellum, 3 a T. harzianum, 1 a T. virens, 1 a T. inhamatum, 1 a...
Tipo: Tesis Palavras-chave: Antagonismo; Antibiosis; Trichoderma spp; Phytophthora parasitica; Jamaica antangonism; Antibiotic; Trichoderma spp.; P. parasitica; Jamaica.
Ano: 2012 URL: http://hdl.handle.net/10521/1029
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Effects on phytoplankton growth of dissolved substances produced by fish farming ArchiMer
Arzul, Genevieve; Clement, Alejandro; Pinier, Anne.
Fish Farming enriches the water column in dissolved organic and inorganic material. These materials excreed by the fish, elutriate from uneaten food and derive from other polluting substances. Ratios of the organic/inorganic forms of substances (for example N and P) are thus modified. Such perturbations in turn affect phytoplankton development. From in vitro analyses and tests of water taken from a turbot rearing tank, we show the changes in seawater chemical composition produced as well as the way growth was modified in three phytoplankton species: the diatom, Chaetoceros gracile, and the dinoflagellates, Gymnodinium cf. nagasakiense and Alexandrium minutum. Elutriates from the granules used for feed (0.1 to 100 mg.l(-1)) were found to be stimulating,...
Tipo: Text Palavras-chave: Antibiotique; Fécès; Aliment; Aquaculture; Régulation de croissance; Phytoplancton; Urée; Antibiotic; Faeces; Feed; Fish farming; Growth regulation; Phytoplankton; Urea.
Ano: 1996 URL: http://archimer.ifremer.fr/doc/00188/29887/28340.pdf
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Employing pharmacokinetic and pharmacodynamic principles to optimize antimicrobial treatment in the face of emerging resistance BJM
Santos Filho,Lauro; Kuti,Joseph L.; Nicolau,David P..
Antimicrobial efficacy in vivo is not exclusively defined by the activity of an antibiotic as determined in the in vitro susceptibility test. Knowledge of the pharmacokinetics and pharmacodynamics of antimicrobials and all phenomena occurring between antimicrobial agents and microorganisms is imperative. The pharmacodynamic (PD) parameters most often used in studies of antibiotic effect include the following relationships: the maximum free concentration (fCmax) to minimum inhibitory concentration (MIC) ratio, the free area under the curve (fAUC/MIC) ratio and the duration of time the free concentration exceeds the MIC (fT>MIC). Utilization of known pharmacokinetic/ pharmacodynamic surrogate relationships should help to optimize treatment outcome,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibiotic; Bacteria; Pharmacodynamics; Resistance.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000200001
Registros recuperados: 36
Primeira ... 12 ... Última
 

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