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Pleiotropic effects of simvastatin in physically trained ovariectomized rats BJMBR
Bernardes,N.; Brito,J.O.; Fernandes,T.G.; Llesuy,S.F.; Irigoyen,M.C.; Belló-Klein,A.; De Angelis,K..
This study tested the hypothesis that simvastatin treatment can improve cardiovascular and autonomic functions and membrane lipoperoxidation, with an increased effect when applied to physically trained ovariectomized rats. Ovariectomized rats were divided into sedentary, sedentary+simvastatin and trained+simvastatin groups (n = 8 each). Exercise training was performed on a treadmill for 8 weeks and simvastatin (5 mg/kg) was administered in the last 2 weeks. Blood pressure (BP) was recorded in conscious animals. Baroreflex sensitivity was evaluated by the tachycardic and bradycardic responses to BP changes. Cardiac vagal and sympathetic effects were determined using methylatropine and propranolol. Oxidative stress was evaluated based on heart and liver...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Menopause; Exercise training; Simvastatin; Autonomic function; Oxidative stress.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000500447
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Ultra-short-term heart rate variability during resistance exercise in the elderly BJMBR
Arêas,G.P.T.; Caruso,F.C.R.; Simões,R.P.; Castello-Simões,V.; Jaenisch,R.B.; Sato,T.O.; Cabiddu,R.; Mendes,R.; Arena,R.; Borghi-Silva,A..
Despite the appeal of ultra-short-term heart rate variability (HRV) methods of analysis applied in the clinical and research settings, the number of studies that have investigated HRV by analyzing R-R interval (RRi) recordings shorter than 5 min is still limited. Moreover, ultra-short-term HRV analysis has not been extensively validated during exercise and, currently, no indications exist for its applicability during resistance exercise. The aim of the present study was to compare ultra-short-term HRV analysis with standard short-term HRV analysis during low-intensity, dynamic, lower limb resistance exercise in healthy elderly subjects. Heart rate (HR) and RRi signals were collected from 9 healthy elderly men during discontinuous incremental resistance...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autonomic function; Older people; Leg press.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000600614
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