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Registros recuperados: 2
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Imprime registro no formato completo
A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom J. Venom. Anim. Toxins incl. Trop. Dis.
Barbosa,Alexandre Naime; Boyer,Leslie; Chippaux,Jean-Philippe; Medolago,Natalia Bronzatto; Caramori,Carlos Antonio; Paixão,Ariane Gomes; Poli,João Paulo Vasconcelos; Mendes,Mônica Bannwart; Santos,Lucilene Delazari dos; Ferreira Jr,Rui Seabra; Barraviera,Benedito.
Abstract Background Envenomation caused by multiple stings from Africanized honeybees Apis mellifera constitutes a public health problem in the Americas. In 2015, the Brazilian Ministry of Health reported 13,597 accidents (incidence of seven cases per 100,000 inhabitants) with 39 deaths (lethality of 0.25%). The toxins present in the venom, which include melittin and phospholipase A2, cause lesions in diverse organs and systems that may be fatal. As there has been no specific treatment to date, management has been symptomatic and supportive only. Methods In order to evaluate the safety and neutralizing capacity of a new apilic antivenom, as well as to confirm its lowest effective dose, a clinical protocol was developed to be applied in a multicenter,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Apis mellifera; Bee venom; Toxins; Envenomation; Heterologous serum; Apilic antivenom; Bee antivenom.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100309
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Honeybee venom: influence of collection on quality and cytotoxicity Ciência Rural
Abrantes,Allyson Fortunato; Rocha,Thayse Cavalcante da; Lima,Amanda Beatriz Sales de; Cavalcanti,Mônica Tejo.
ABSTRACT: Apitoxin is the venom produced by bees. It is a complex chemical compound, rich in protein substances and with pharmacological effects. This study was carried out with the objective of comparing the quality of apitoxin extracted in an apiary in different parts of the collector in relation to moisture content, protein analysis and cytotoxicity assay with Artemia salina L. Type 1 apitoxin was collected from glass slabs at the entrance to the hive, while type 2 apitoxin was collected from the waste accumulated in the collection rods and treated by rinsing in distilled water. Both apitoxins presented significant differences (P>0.05) in relation to protein profile, with type 1 showing a higher content (77.8%) than type 2 (51.9%), and presented...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bees; Beekeeping; Bee venom; Artemia salina L.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001000401
Registros recuperados: 2
Primeira ... 1 ... Última
 

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